Evidence map›Paper›PMID 29371577›Full record

ReviewJournal of fungi (Basel, Switzerland)2017

MCC/Eisosomes Regulate Cell Wall Synthesis and Stress Responses in Fungi.

Jenna E Foderaro, Lois M Douglas, James B Konopka

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Predicted Structure ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Inducible degradation-coupled phosphoproteomics identifies PP2AFrontiers in cell and developmental biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Complementation of an Eisosomal YeastJournal of fungi (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity.Journal of fungi (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Article
  18. Scalar nanostructure of theCell surface (Amsterdam, Netherlands) · 2020
    Article
  19. Plasma Membrane MCC/Eisosome Domains Promote Stress Resistance in Fungi.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jenna E FoderaroDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA. jenna.foderaro@stonybrook.edu.
Lois M DouglasDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA. lmardouglas@gmail.com.
James B KonopkaDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA. james.konopka@stonybrook.edu.
Stony Brook University · US

Funding

Regulation of Morphogenesis in C. albicansR01AI047837 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI James B Konopka · 2001 to 2026
$8.8M
Signal pathways controlling the bud to hypha transitionR01GM116048 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI KONOPKA, JAMES B · 2015 to 2022
$2.5M
NIAID NIH HHS R01 AI047837NIGMS NIH HHS R01 GM116048
6 · The paper itself

Abstract

The fungal plasma membrane is critical for cell wall synthesis and other important processes including nutrient uptake, secretion, endocytosis, morphogenesis, and response to stress. To coordinate these diverse functions, the plasma membrane is organized into specialized compartments that vary in size, stability, and composition. One recently identified domain known as the Membrane Compartment of Can1 (MCC)/eisosome is distinctive in that it corresponds to a furrow-like invagination in the plasma membrane. MCC/eisosomes have been shown to be formed by the Bin/Amphiphysin/Rvs (BAR) domain proteins Lsp1 and Pil1 in a range of fungi. MCC/eisosome domains influence multiple cellular functions; but a very pronounced defect in cell wall synthesis has been observed for mutants with defects in MCC/eisosomes in some yeast species. For example,

Indexed as

Candida albicanscell wallchitineisosomefungalMembrane Compartment of Can1 (MCC) domainmorphogenesisβ-glucan

Identifiers

PMID29371577
PMCPMC5753163
OpenAlexW2766506969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.