Evidence map›Paper›PMID 29371572›Full record

ReviewJournal of fungi (Basel, Switzerland)2017

The Human Mucosal Mycobiome and Fungal Community Interactions.

Elizabeth A Witherden, Saeed Shoaie, Rebecca A Hall, David L Moyes

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Fecal transplantation for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Article
  3. mBio · 2026
    Article
  4. Article
  5. BeyondJournal of fungi (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Fungal translocation measured by serum 1,3-ß-D-glucan correlates with severity and outcome of liver cirrhosis-A pilot study.Liver international : official journal of the International Association for the Study of the Liver · 2023
    Article
  16. Fecal transplantation for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2023
    Review
  17. Roles ofFrontiers in cellular and infection microbiology · 2023
    Review
  18. Review
  19. Review
  20. Role of Cellular Metabolism duringPathogens (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth A WitherdenCentre for Host-Microbiome Interactions, Dental Institute, King's College London, London SE1 9RT, UK. elizabeth.witherden@kcl.ac.uk.ORCID 0000-0002-7391-9371
Saeed ShoaieCentre for Host-Microbiome Interactions, Dental Institute, King's College London, London SE1 9RT, UK. saeed.shoaie@kcl.ac.uk.
Rebecca A HallInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK. r.a.hall@bham.ac.uk.
David L MoyesCentre for Host-Microbiome Interactions, Dental Institute, King's College London, London SE1 9RT, UK. david.moyes@kcl.ac.uk.

Funding

Host and Fungal Regulation of Type 17 Immunity to Oral CandidiasisR37DE022550 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sarah L Gaffen · 2017 to 2026
$5.6M
Medical Research Council MR/L00903X/1NIDCR NIH HHS R37 DE022550
6 · The paper itself

Abstract

With the advent of high-throughput sequencing techniques, the astonishing extent and complexity of the microbial communities that reside within and upon us has begun to become clear. Moreover, with advances in computing and modelling methods, we are now beginning to grasp just how dynamic our interactions with these communities are. The diversity of both these communities and their interactions-both within the community and with us-are dependent on a multitude of factors, both microbial- and host-mediated. Importantly, it is becoming clear that shifts in the makeup of these communities, or their responses, are linked to different disease states. Although much of the work to define these interactions and links has been investigating bacterial communities, recently there has been significant growth in the body of knowledge, indicating that shifts in the host fungal communities (mycobiome) are also intimately linked to disease status. In this review, we will explore these associations, along with the interactions between fungal communities and their human and microbial habitat, and discuss the future applications of systems biology in determining their role in disease status.

Indexed as

bacterial-fungal interactionsfungal-fungal interactionshost-fungal interactionsmicrobiomemycobiomesystems biology

Identifiers

PMID29371572
PMCPMC5753158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.