Evidence map›Paper›PMID 29371545›Full record

ArticleJournal of fungi (Basel, Switzerland)2017

MIC Distributions and Evaluation of Fungicidal Activity for Amphotericin B, Itraconazole, Voriconazole, Posaconazole and Caspofungin and 20 Species of Pathogenic Filamentous Fungi Determined Using the CLSI Broth Microdilution Method.

Andrew M Borman, Mark Fraser, Michael D Palmer, Adrien Szekely, Marian Houldsworth, Zoe Patterson, Elizabeth M Johnson

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Establishment of epidemiological cutoff values againstJournal of clinical microbiology · 2026
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  7. First case of invasiveMedical mycology case reports · 2024
    Article
  8. Does sorghum phenolic extract have antifungal effect?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Molecules (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Antimicrobial agents and chemotherapy · 2022
    Article
  15. Article
  16. Recent Advances and Future Directions in the Understanding of Mucormycosis.Frontiers in cellular and infection microbiology · 2022
    Review
  17. Article
  18. First Report of a Case of Ocular Infection Caused byPathogens (Basel, Switzerland) · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew M BormanPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. andrew.borman@phe.gov.uk.
Mark FraserPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. mark.fraser@phe.gov.uk.
Michael D PalmerPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. michael.palmer@phe.gov.uk.
Adrien SzekelyPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. adrien.szekely@phe.gov.uk.
Marian HouldsworthPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. marian.houldsworth@phe.gov.uk.
Zoe PattersonPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. zoe.patterson@phe.gov.uk.
Elizabeth M JohnsonPublic Health England United Kingdom, Mycology Reference Laboratory, Myrtle Road, Bristol BS2 8EL, UK. elizabeth.johnson@phe.gov.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For filamentous fungi (moulds), species-specific interpretive breakpoints and epidemiological cut-off values (ECVs) have only been proposed for a limited number of fungal species-antifungal agent combinations, with the result that clinical breakpoints are lacking for most emerging mould pathogens. In the current study, we have compiled minimum inhibitory concentration (MIC) data for 4869 clinical mould isolates and present full MIC distributions for amphotericin B, itraconazole, voriconazole, posaconazole, and caspofungin with these isolates which comprise 20 species/genera. In addition, we present the results of an assessment of the fungicidal activity of these same five antifungal agents against a panel of 123 mould isolates comprising 16 of the same species.

Indexed as

amphotericin BcaspofunginECVsfilamentous fungifungicidalitraconazoleposaconazolesusceptibility testingvoriconazolewild-type distributions

Identifiers

PMID29371545
PMCPMC5715917

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.