ArticleBMJ open2018
Association between body mass index and obesity-related cancer risk in men and women with type 2 diabetes in primary care in the Netherlands: a cohort study (ZODIAC-56).
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Body mass index and cancer risk in patients with type 2 diabetes: a dose-response meta-analysis of cohort studies.Scientific reports · 2021Pooled it
- The association between IGF1 gene rs1520220 polymorphism and cancer susceptibility: a meta-analysis based on 12,884 cases and 58,304 controls.Environmental health and preventive medicine · 2018Pooled it
- Association between body mass index, metabolic syndrome and common urologic conditions: a cross-sectional study using a large multi-institutional database from the United States.Annals of medicine · 2023Article
- Body Mass Index is Associated with blood pressure and vital capacity in medical students.Lipids in health and disease · 2023Article
- Epidemiology and Prevention of Renal Cell Carcinoma.Cancers · 2022Review
- Weight Changes in Type 2 Diabetes and Cancer Risk: A Latent Class Trajectory Model Study.Obesity facts · 2022Article
- Nomogram Model for Prediction of Portal Vein Thrombosis in Patients with Liver Cirrhosis After Splenectomy: A Retrospective Analysis of 2 Independent Cohorts.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Sex disparities matter in cancer development and therapy.Nature reviews. Cancer · 2021Review
- Association between insulin-like growth factor 1 gene rs5742612 polymorphism and malignant tumor susceptibility: a meta-analysis.Translational cancer research · 2021Article
- Observation of Efficacy of Internet-Based Chronic Disease Management Model Combined with Modified Therapy of Bushenyiliu Decoction in Treating Patients with Type 2 Diabetes Mellitus and Prostate Cancer and Its Effect on Disease Control Rate.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Measuring growth and medium- and longer-term outcomes in malnourished children.Maternal & child nutrition · 2019Review
- Epidemiology of Renal Cell Carcinoma.European urology · 2019Review
- Body mass index and cancer risk among Chinese patients with type 2 diabetes mellitus.BMC cancer · 2018Article
- First-in-Class Oral Semaglutide: Overcoming Barriers of Incretinisation in the Indian Context.Indian journal of endocrinology and metabolismReview
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the relationship between body mass index (BMI) and obesity-related cancers in men and women with type 2 diabetes (T2D).
designObservational cohort study.
settingPrimary care.
participantsA total of 52 044 patients with T2D who participated in the ZODIAC (Zwolle Outpatient Diabetes project Integrating Available Care) study between 1998 and 2012 was included (49% women). A dataset of these patients was linked to available information of the Netherlands Cancer Registry to obtain data on cancer incidents. PRIMARY OUTCOME MEASURES: Analyses were performed for the total group of obesity-related cancers and for non-sex-specific and sex-specific obesity-related cancers (in men: advanced prostate cancer, in women: ovarian, endometrial and postmenopausal breast cancer).
resultsThe median follow-up period in all analyses was 3.1 (1.7-5.0) years in men and 3.1 (1.7-5.1) in women. During follow-up, 689 men and 914 women were diagnosed with an obesity-related cancer. In men, BMI was associated with a higher risk of the total group of obesity-related cancers and non-sex-specific obesity-related cancers (HR (per 5 kg/m
conclusionsBMI is associated with obesity-related cancers in men with T2D, except with advanced prostate cancer. The results of this study provide reason to reconsider the classification of advanced prostate cancer as an obesity-related cancer, at least in T2D. In women, BMI is associated with the total group of obesity-related cancers and with sex-specific obesity-related cancers.
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