ArticleAJNR. American journal of neuroradiology2018
Comparison of MR Imaging and Dual-Energy CT for the Evaluation of Cartilage Invasion by Laryngeal and Hypopharyngeal Squamous Cell Carcinoma.
Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603167 (p-PHOTOLARYNX- ANTHEM), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
p-PHOTOLARYNX- ANTHEM: Pilot Photon-Counting CT Evaluation of the Paraglottic Space and Cartilage Involvement in Laryngeal Cancer
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of diagnostic performance between CT and MRI for detection of cartilage invasion for primary tumor staging in patients with laryngo-hypopharyngeal cancer: a systematic review and meta-analysis.European radiology · 2020Pooled it
- Practical applications of photon-counting CT in oncology: an organ-based pictorial review.Insights into imaging · 2026Article
- Glottic tumours involving the anterior commissure in a horizontal vs vertical mode have different prognosis. Opportunity for refinement of the TNM 8Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026Review
- Multimodal deep learning for laryngeal squamous cell carcinoma staging using CT and laryngoscopy.European radiology · 2026Article
- Contemporary Indications and Technical Limits of Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.Advances in therapy · 2026Review
- Imaging-detected extranodal extension in head and neck cancer: clinical implications, diagnostic criteria, and the potential of photon-counting detector CT.Japanese journal of radiology · 2026Review
- CT-based texture analysis for preoperative prediction of key histopathological features in laryngeal cancer.Polish journal of radiology · 2026Article
- Diagnostic value, sensitivity and specificity of CT, MRI, and PET in evaluation of cartilage invasion in laryngeal and hypopharyngeal cancer.Scientific reports · 2025Article
- Postoperative CT and Functional Analysis of New Larynx in Different Supracricoid Partial Laryngectomy Procedures.Laryngoscope investigative otolaryngology · 2025Article
- Time-Intensity Curve Analysis of Contrast-Enhanced Ultrasound for Non-Ossified Thyroid Cartilage Invasion in Laryngeal Squamous Cell Carcinoma.Tomography (Ann Arbor, Mich.) · 2025Article
- Head and Neck Squamous Cell Carcinoma: Insights from Dual-Energy Computed Tomography (DECT).Tomography (Ann Arbor, Mich.) · 2024Review
- Article
- Thyroid cartilage infiltration in advanced laryngeal cancer: prognostic implications and predictive modelling.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2024Article
- Discrepancy between clinical and pathological staging of laryngeal carcinoma: a dilemma to be solved.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- An MRI-based radiomics nomogram for detecting cervical esophagus invasion in hypopharyngeal squamous cell carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- CT of the Larynx: Is an Additional High-Resolution Acquisition Necessary for Diagnostic Accuracy?AJNR. American journal of neuroradiology · 2023Article
- Imaging for Laryngeal Malignancies: Guidelines for Clinicians.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Dual-energy CT for the detection of skull base invasion in nasopharyngeal carcinoma: comparison of simulated single-energy CT and MRI.Insights into imaging · 2023Article
- Dual-energy CT iodine map in predicting the efficacy of neoadjuvant chemotherapy for hypopharyngeal carcinoma: a preliminary study.Scientific reports · 2022Article
- Magnetic resonance imaging to assess cartilage invasion in recurrent laryngeal carcinoma after transoral laser microsurgery.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2022Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDual-energy CT can distinguish iodine-enhanced tumors from nonossified cartilage and has been investigated for evaluating cartilage invasion in patients with laryngeal and hypopharyngeal squamous cell carcinomas. In this study, we compared the diagnostic accuracy of MR imaging and of a combination of weighted-average and iodine overlay dual-energy CT images in detecting cartilage invasion by laryngeal and hypopharyngeal squamous cell carcinomas, in particular thyroid cartilage invasion. MATERIALS AND
methodsFifty-five consecutive patients who underwent 3T MR imaging and 128-slice dual-energy CT for preoperative initial staging of laryngeal or hypopharyngeal squamous cell carcinomas were included. Two blinded observers evaluated laryngeal cartilage invasion on MR imaging and dual-energy CT using a combination of weighted-average and iodine-overlay images. Pathologic findings of surgically resected specimens were used as the reference standard for evaluating sensitivity, specificity, and the areas under the receiver operating characteristic curve of both modalities for cartilage invasion by each type of cartilage and for all cartilages together. Sensitivity and specificity were compared using the McNemar test and generalized linear mixed models.
resultsDual-energy CT showed higher specificity than MR imaging for diagnosing all cartilage together (84% for MR imaging versus 98% for dual-energy CT,
conclusionsDual-energy CT showed higher specificity and acceptable sensitivity in diagnosing laryngeal cartilage invasion compared with MR imaging.
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