ArticleBMC genomics2018
Association mapping for total polyphenol content, total flavonoid content and antioxidant activity in barley.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
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- Phenolic compounds, antioxidant enzymes, and oxidative stress in barley (Hordeum vulgare L.) genotypes under field drought-stress conditions.BMC plant biology · 2025Article
- Callus Culture System fromInternational journal of molecular sciences · 2025Article
- Role of total polyphenol content in seed germination characteristics of spring barley varieties amidst climate change.Scientific reports · 2024Article
- Physiological Mechanisms by Which the Functional Ingredients in Beer Impact Human Health.Molecules (Basel, Switzerland) · 2024Review
- Exogenous Melatonin Enhances Dihydrochalcone Accumulation inInternational journal of molecular sciences · 2024Article
- Functional characterization of a cold related flavanone 3-hydroxylase from Tetrastigma hemsleyanum: an in vitro, in silico and in vivo study.Biotechnology letters · 2023Article
- Proteome Changes Resulting from Malting in Hordein-Reduced Barley Lines.Journal of agricultural and food chemistry · 2023Article
- Genome-Wide Association Study of Phenolic Content and Antioxidant Properties in Eggplant Germplasm.Genes · 2023Article
- Influence of Cultivar and Turbidity on Physicochemical Properties, Functional Characteristics and Volatile Flavor Substances of Pomelo Juices.Foods (Basel, Switzerland) · 2023Article
- Development of SNP Markers from GWAS for Selecting Seed Coat and Aleurone Layers in Brown Rice (Genes · 2022Article
- Polyphenol and Anthocyanin Composition and Activity of Highland Barley with Different Colors.Molecules (Basel, Switzerland) · 2022Article
- Genome-Wide Association Study of Healthful Flavonoids among Diverse Mandarin Accessions.Plants (Basel, Switzerland) · 2022Article
- Phenotypic and molecular analyses in diploid and tetraploid genotypes ofFrontiers in plant science · 2022Article
- A multi-locus genome-wide association study reveals the genetics underlying muscadine antioxidant in berry skin.Frontiers in plant science · 2022Article
- A Correlation Study on In Vitro Physiological Activities of Soybean Cultivars, 19 Individual Isoflavone Derivatives, and Genetic Characteristics.Antioxidants (Basel, Switzerland) · 2021Article
- Phylogeography and Antioxidant Activity of Proso Millet (Plants (Basel, Switzerland) · 2021Article
- The Role of Bioactive Phenolic Compounds on the Impact of Beer on Health.Molecules (Basel, Switzerland) · 2021Review
- Omics Technologies to Enhance Plant Based Functional Foods: An Overview.Frontiers in genetics · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe interest has been increasing on the phenolic compounds in plants because of their nutritive function as food and the roles regulating plant growth. However, their underlying genetic mechanism in barley is still not clear.
resultsA genome-wide association study (GWAS) was conducted for total phenolic content (TPC), total flavonoid content (FLC) and antioxidant activity (AOA) in 67 cultivated and 156 Tibetan wild barley genotypes. Most markers associated with phenolic content were different in cultivated and wild barleys. The markers bPb-0572 and bPb-4531 were identified as the major QTLs controlling phenolic compounds in Tibetan wild barley. Moreover, the marker bPb-4531 was co-located with the UDP- glycosyltransferase gene (HvUGT), which is a homolog to Arabidopsis UGTs and involved in biosynthesis of flavonoid glycosides .
conclusionsGWAS is an efficient tool for exploring the genetic architecture of phenolic compounds in the cultivated and Tibetan wild barleys. The DArT markers applied in this study can be used in barley breeding for developing new barley cultivars with higher phenolics content. The candidate gene (HvUGT) provides a potential route for deep understanding of the molecular mechanism of flavonoid synthesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.