Evidence map›Paper›PMID 29370477›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Prevalence and clinical outcomes of white-coat and masked hypertension: Analysis of a large ambulatory blood pressure database.

Giuliano Tocci, Vivianne Presta, Ilaria Figliuzzi, Nadia Attalla El Halabieh, Allegra Battistoni, Roberta Coluccia, Michela D'Agostino, Andrea Ferrucci, Massimo Volpe

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Lipoprotein(a) in Essential Hypertension: Associations with Blood Pressure and Hypertension-Mediated Organ Damage.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Observational
  5. Article
  6. Article
  7. Article
  8. Blood Pressure Target Achievement Under Monotheraphy: A Real-Life Appraisal.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Observational
  9. Article
  10. Epidemiological Impact and Clinical Consequences of Masked Hypertension: A Narrative Review.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Review
  11. Review
  12. Effects of white-coat, masked and sustained hypertension on coronary artery stenosis and cardiac arrhythmia.Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Observational
  13. White-coat and masked hypertension and coronary artery disease: are they related or not?Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Article
  14. Clinical applications for out-of-office blood pressure monitoring.Therapeutic advances in chronic disease · 2020
    Review
  15. Article
  16. Temporary hypertension and white coat hypertension in the first trimester as risk factors for preeclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  17. Observational
  18. Association of thyroid function with white coat hypertension and sustained hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giuliano TocciDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.ORCID 0000-0002-0635-4921
Vivianne PrestaDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.
Ilaria FigliuzziDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.
Nadia Attalla El HalabiehDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.
Allegra BattistoniDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.
Roberta ColucciaIRCCS Neuromed, Pozzilli, Italy.
Michela D'AgostinoDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.
Andrea FerrucciDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.
Massimo VolpeDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital University of Rome Sapienza, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to analyze prevalence and clinical outcomes of the following clinical conditions: normotension (NT; clinic BP < 140/90 mm Hg; 24-hour BP < 130/80 mm Hg), white-coat hypertension (WCHT; clinic BP ≥ 140 and/or ≥90 mm Hg; 24-hour BP < 130/80 mm Hg), masked hypertension (MHT; clinic BP < 140/90 mm Hg; 24-hour BP ≥ 130 and/or ≥80 mm Hg), and sustained hypertension (SHT; clinic BP ≥ 140 and/or ≥90 mm Hg; 24-hour BP ≥ 130 and/or ≥80 mm Hg) in a large cohort of adult untreated individuals. Systematic research throughout the medical database of Regione Lazio (Italy) was performed to estimate incidence of myocardial infarction (MI), stroke, and hospitalizations for HT and heart failure (HF). Among a total study sample of 2209 outpatients, 377 (17.1%) had NT, 351 (15.9%) had WCHT, 149 (6.7%) had MHT, and 1332 had (60.3%) SHT. During an average follow-up of 120.1 ± 73.9 months, WCHT was associated with increased risk of hospitalization for HT (OR 95% CI: 1.927 [1.233-3.013]; P = .04) and HF (OR 95% CI: 3.449 [1.321-9.007]; P = .011). MHT was associated with an increased risk of MI (OR 95% CI: 5.062 [2.218-11.550]; P < .001), hospitalization for HT (OR 95% CI: 2.553 [1.446-4.508]; P = .001), and for HF (OR 95% CI: 4.214 [1.449-12.249]; P = .008). These effects remained statistically significant event after corrections for confounding factors including age, BMI, gender, smoking, dyslipidaemia, diabetes, and presence of antihypertensive therapies.

Indexed as

Blood Pressure Monitoring, AmbulatoryMasked HypertensionWhite Coat HypertensionAntihypertensive AgentsBlood PressureCohort StudiesDatabases, FactualFemaleHospitalizationHumansIncidenceItalyMaleMiddle AgedMyocardial InfarctionPrevalenceAntihypertensive Agentsambulatory blood pressure monitoringhospitalizationsmasked hypertensionmyocardial infarctionstrokesustained hypertensionwhite-coat hypertension

Identifiers

PMID29370477
PMCPMC8031207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.