Evidence map›Paper›PMID 29370469›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Central blood pressure variability is increased in hypertensive patients with target organ damage.

Alejandro de la Sierra, Julia Pareja, Sergi Yun, Eva Acosta, Francesco Aiello, Anna Oliveras, Susana Vázquez, Pedro Armario, Pedro Blanch, Cristina Sierra and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Alejandro de la SierraDepartment of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain.ORCID 0000-0002-6548-5497
Julia ParejaDepartment of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain.
Sergi YunDepartment of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain.
Eva AcostaDepartment of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain.
Francesco AielloDepartment of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain.
Anna OliverasDepartment of Nephrology, Hospital del Mar, Barcelona, Spain.
Susana VázquezDepartment of Nephrology, Hospital del Mar, Barcelona, Spain.
Pedro ArmarioCardiovascular Disease Unit, Hospital Moisés Broggi Sant Joan Despí, Spain.
Pedro BlanchCardiovascular Disease Unit, Hospital Moisés Broggi Sant Joan Despí, Spain.
Cristina SierraDepartment of Internal Medicine, Hospital Clínic, Barcelona, Spain.
Francesca CaleroRenal and Hypertension Units, Fundació Puigvert Universitat Autónoma de Barcelona, Barcelona, Spain.
Patricia Fernández-LlamaRenal and Hypertension Units, Fundació Puigvert Universitat Autónoma de Barcelona, Barcelona, Spain.
University Hospital Mútua de Terrassa · ESHospital Del Mar · ESHospital de Sant Joan Despí Moisès Broggi · ESUniversitat Autònoma de Barcelona · ESHospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to evaluate the association of aortic and brachial short-term blood pressure variability (BPV) with the presence of target organ damage (TOD) in hypertensive patients. One-hundred seventy-eight patients, aged 57 ± 12 years, 33% women were studied. TOD was defined by the presence of left ventricular hypertrophy on echocardiogram, microalbuminuria, reduced glomerular filtration rate, or increased aortic pulse wave velocity. Aortic and brachial BPV was assessed by 24-hour ambulatory BP monitoring (Mobil-O-Graph). TOD was present in 92 patients (51.7%). Compared to those without evidence of TOD, they had increased night-to-day ratios of systolic and diastolic BP (both aortic and brachial) and heart rate. They also had significant increased systolic BPV, as measured by both aortic and brachial daytime and 24-hours standard deviations and coefficients of variation, as well as for average real variability. Circadian patterns and short-term variability measures were very similar for aortic and brachial BP. We conclude that BPV is increased in hypertensive-related TOD. Aortic BPV does not add relevant information in comparison to brachial BPV.

Indexed as

HypertensionAgedAnalysis of VarianceArterial PressureBlood Pressure Monitoring, AmbulatoryBrachial ArteryCircadian RhythmCorrelation of DataEchocardiographyFemaleGlomerular Filtration RateHeart RateHumansMaleMiddle AgedPulse Wave Analysisambulatory blood pressure monitoringaortic blood pressureblood pressure variabilitycentral blood pressurecircadian blood pressure profileorgan damage

Identifiers

PMID29370469
PMCPMC8030748
OpenAlexW2791418098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.