Evidence map›Paper›PMID 29370468›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Association of ambulatory blood pressure variability with coronary artery calcium.

Bailey DeBarmore, Feng-Chang Lin, Laura A Tuttle, Emily Olsson, Alan Hinderliter, Jeffrey L Klein, Anthony J Viera

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Subclinical cardiovascular disease and utility of coronary artery calcium score.International journal of cardiology. Heart & vasculature · 2021
    Review
  3. Article
  4. Blood pressure variability: Prognostic implications in low-risk subjects.Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
  5. Article
  6. Association of ambulatory blood pressure variability with coronary artery calcium.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bailey DeBarmoreDepartment of Epidemiology, Gillings School of Global, Public Health University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-9911-0917
Feng-Chang LinDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Laura A TuttleDepartment of Family Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Emily OlssonDepartment of Family Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Alan HinderliterDepartment of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jeffrey L KleinDepartment of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Anthony J VieraDepartment of Family Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0001-5770-2052
University of North Carolina at Chapel Hill · US

Funding

UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Reproducibility and Clinical Implications of Masked HypertensionR01HL098604 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VIERA, ANTHONY J · 2010 to 2012
$1.9M
NCRR NIH HHS UL1 RR025747NHLBI NIH HHS R01 HL098604NHLBI NIH HHS T32 HL007055
6 · The paper itself

Abstract

Blood pressure (BP) variability is associated with progression to clinical atherosclerosis. The evidence is inconclusive if BP variability predicts cardiovascular outcomes in low-risk populations. The aim of this study was to analyze the association of 24-hour BP variability with coronary artery calcium (CAC) among a group of individuals without coronary artery disease. The Masked Hypertension Study targeted patients with borderline high BP (120-149 mm Hg systolic and/or 80-95 mm Hg diastolic). Ambulatory blood pressure monitoring (ABPM) was performed at two time-points, 8 days apart. CAC was measured at exit visit via cardiac CT and reported as Agatston Score. Weighted standard deviations and average real variability were calculated from ABPM. Of the 322 participants who underwent cardiac CT, 26% (84) had CAC present, 52% (168) were female, and 21% (64) were black. BP variability did not differ by CAC group. In this low cardiovascular risk group, CAC was not associated with 24-hour ambulatory BP variability.

Indexed as

CalciumCoronary Artery DiseaseCoronary VesselsMasked HypertensionAdultAgedAnalysis of VarianceBlood PressureBlood Pressure Monitoring, AmbulatoryCorrelation of DataFemaleHumansMaleMiddle AgedRisk FactorsUnited StatesCalciumambulatory blood pressureblood pressure monitoringblood pressure variabilitycoronary artery calcium

Identifiers

PMID29370468
PMCPMC5820162
OpenAlexW2789620131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.