Evidence map›Paper›PMID 29370178›Full record

Observational studyPloS one2018

General Practitioner trainers prescribe fewer antibiotics in primary care: Evidence from France.

Louise Devillers, Jonathan Sicsic, Angelique Delbarre, Josselin Le Bel, Emilie Ferrat, Olivier Saint Lary

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04513938 (Interest of the Second Phase of the Oral Challenge Test in Patients With Suspected Long-standing Penicillin Allergy), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04513938 completednot on this mapstarted 2020, after this paper: background citation

Interest of the Second Phase of the Oral Challenge Test in Patients With Suspected Long-standing Penicillin Allergy

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2020 to 2023Enrolled195ConditionsAllergy Penicillin
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Antimicrobial resistance profiles ofJAC-antimicrobial resistance · 2024
    Article
  4. Article
  5. Article
  6. Yonder: GP trainers, menopause, shared decision making, and coroners' reports.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Louise DevillersDepartment of Family Medicine, Faculty of Health Sciences Simone Veil, University Versailles Saint-Quentin en Yvelines (UVSQ), Montigny-le-Bretonneux, France.ORCID 0000-0001-9086-300X
Jonathan SicsicCESP, University Paris-Sud, UVSQ, INSERM U1018, University Paris-Saclay, Villejuif, France.
Angelique DelbarreCESP, University Paris-Sud, UVSQ, INSERM U1018, University Paris-Saclay, Villejuif, France.
Josselin Le BelDepartment of Family Medicine, University Paris Diderot, Sorbonne Paris Cité, Paris, France.
Emilie FerratUniversity Paris-Est Créteil (UPEC), School of Medicine, Primary Care Department, Créteil, France.
Olivier Saint LaryDepartment of Family Medicine, Faculty of Health Sciences Simone Veil, University Versailles Saint-Quentin en Yvelines (UVSQ), Montigny-le-Bretonneux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAntibiotic prescription is a central public health issue. Overall, 90% of antibiotic prescriptions are delivered to patients in ambulatory care, and a substantial proportion of these prescriptions could be avoided. General Practitioner (GP) trainers are similar to other GPs in terms of sociodemographic and medical activities, but they may have different prescription patterns. Our aim was to compare the antibiotic prescribing rates between GP trainers and non-trainers.

methodsThis observational cross-sectional study was conducted on administrative data claims from the French National Health Insurance. The antibiotic prescribing rate was calculated. The main independent variable was the training status of the GPs. Prescribing rates were adjusted for the various GPs' characteristics (gender, age, location of the practice, number of visits per GP and the case-mix) in a multiple linear regression analysis.

resultsBetween June 2014 and July 2015 the prescribing patterns of 860 GPs were analysed, among which 102 were GP trainers (12%). Over the year 363,580 patients were prescribed an antibiotic out of 3,499,248 visits for 1,299,308 patients seen over the year thus representing around 27.5% of patients. In the multivariate analyses, being a trainer resulted in a significant difference of 6.62 percentage points (IC 95%: [-8.55; -4.69]; p<0.001) in antibiotic prescriptions comparing to being a non-trainer, corresponding to a relative reduction of 23.4%.

conclusionThese findings highlight the role of GP trainers in antibiotic prescriptions. By prescribing fewer antibiotics and influencing the next generations of GPs, the human and economic burden of antibiotics could be reduced.

Indexed as

Drug Utilization ReviewGeneral PractitionersAnti-Bacterial AgentsCross-Sectional StudiesFemaleFranceHumansMaleMiddle AgedPrimary Health CareAnti-Bacterial Agents

Identifiers

PMID29370178
PMCPMC5784911

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.