ArticlePLoS genetics2018
Insular Celtic population structure and genomic footprints of migration.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- Genetic ancestry and monogenic disease risk in the Scottish Traveller founder population.Nature communications · 2026Article
- Whole-Genome Sequencing in Galicia Reveals Male-Biased Pre-Islamic North African Ancestry, Subtle Population Structure, and Microgeographic Patterns of Disease Risk.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- A genetic perspective on the recent demographic history of Ireland and Britain.European journal of human genetics : EJHG · 2025Article
- Donor genetic burden for cerebrovascular risk and kidney transplant outcome.Journal of nephrology · 2024Article
- Genetic diversity and historical demography of underutilised goat breeds in North-Western Europe.Scientific reports · 2023Article
- The Newfoundland and Labrador mosaic founder population descends from an Irish and British diaspora from 300 years ago.Communications biology · 2023Article
- Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK.PLoS genetics · 2023Article
- Millennium-old pathogenic Mendelian mutation discovery for multiple osteochondromas from a Gaelic Medieval graveyard.European journal of human genetics : EJHG · 2023Article
- New insights on Celtic migration in Hungary and Italy through the analysis of non-metric dental traits.PloS one · 2023Article
- Fitness and Power: The Contribution of Genetics to the History of Differential Reproduction.Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior · 2021Article
- Comparisons of disease cluster patterns, prevalence and health factors in the USA, Canada, England and Ireland.BMC public health · 2021Article
- Evidence of the interplay of genetics and culture in Ethiopia.Nature communications · 2021Article
- Fine-Scale Genetic Structure and Demographic History in the Miyako Islands of the Ryukyu Archipelago.Molecular biology and evolution · 2021Article
- Changes in the fine-scale genetic structure of Finland through the 20th century.PLoS genetics · 2021Article
- Genetic diversity and phylogenetic relationship of nine sheep populations based on microsatellite markers.Archives animal breeding · 2021Article
- The future of genomics in Ireland - focus on genomics for health.HRB open research · 2020Article
- Association Between Glucocerebrosidase Mutations and Parkinson's Disease in Ireland.Frontiers in neurology · 2020Article
- The genetic landscape of Scotland and the Isles.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe.Science advances · 2019Article
- Genotyping-by-Sequencing ofEvolutionary bioinformatics online · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Previous studies of the genetic landscape of Ireland have suggested homogeneity, with population substructure undetectable using single-marker methods. Here we have harnessed the haplotype-based method fineSTRUCTURE in an Irish genome-wide SNP dataset, identifying 23 discrete genetic clusters which segregate with geographical provenance. Cluster diversity is pronounced in the west of Ireland but reduced in the east where older structure has been eroded by historical migrations. Accordingly, when populations from the neighbouring island of Britain are included, a west-east cline of Celtic-British ancestry is revealed along with a particularly striking correlation between haplotypes and geography across both islands. A strong relationship is revealed between subsets of Northern Irish and Scottish populations, where discordant genetic and geographic affinities reflect major migrations in recent centuries. Additionally, Irish genetic proximity of all Scottish samples likely reflects older strata of communication across the narrowest inter-island crossing. Using GLOBETROTTER we detected Irish admixture signals from Britain and Europe and estimated dates for events consistent with the historical migrations of the Norse-Vikings, the Anglo-Normans and the British Plantations. The influence of the former is greater than previously estimated from Y chromosome haplotypes. In all, we paint a new picture of the genetic landscape of Ireland, revealing structure which should be considered in the design of studies examining rare genetic variation and its association with traits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.