Evidence map›Paper›PMID 29370069›Full record

ArticleInternational journal of molecular sciences2018

Tauroursodeoxycholic Acid Protects against the Effects of P-Cresol-Induced Reactive Oxygen Species via the Expression of Cellular Prion Protein.

Seung Pil Yun, Yeo Min Yoon, Jun Hee Lee, Minjee Kook, Yong-Seok Han, Seo Kyung Jung, Sang Hun Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Development of biomaterials for bone tissue engineering based on bile acids.Journal of materials science. Materials in medicine · 2025
    Review
  5. Review
  6. Review
  7. Treatment ofFrontiers in cell and developmental biology · 2021
    Article
  8. Knockdown of CK2α reducesInternational journal of medical sciences · 2020
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Pioglitazone Protects Mesenchymal Stem Cells againstInternational journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Seung Pil YunDepartment of Neurology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. spyun1002@gmail.com.
Yeo Min YoonInstitute of Soonchunhyang Medical Science Research, Soonchunhyang University Hospital Seoul, Soonchunhyang University, Seoul 04401, Korea. yoonboo15@naver.com.
Jun Hee LeeDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA. j-school@hanmail.net.
Minjee KookDepartment of Neurology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. mkook2@jhu.edu.
Yong-Seok HanInstitute of Soonchunhyang Medical Science Research, Soonchunhyang University Hospital Seoul, Soonchunhyang University, Seoul 04401, Korea. format7000@naver.com.
Seo Kyung JungInstitute of Soonchunhyang Medical Science Research, Soonchunhyang University Hospital Seoul, Soonchunhyang University, Seoul 04401, Korea. 3569123@naver.com.
Sang Hun LeeInstitute of Soonchunhyang Medical Science Research, Soonchunhyang University Hospital Seoul, Soonchunhyang University, Seoul 04401, Korea. ykckss1114@nate.com.ORCID 0000-0002-6713-8229
Soonchunhyang University Hospital Seoul · KRJohns Hopkins University · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) could be a promising solution in the treatment of various diseases including chronic kidney disease (CKD). However, endoplasmic reticulum (ER) stress induced by ischemia in the area of application limits the integration and survival of MSCs in patients. In our study, we generated ER stress-induced conditions in MSCs using

Indexed as

Adipose TissueAntioxidantsApoptosisCells, CulturedCresolsEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressHumansMesenchymal Stem CellsOxidative StressPrPC ProteinsReactive Oxygen SpeciesTaurochenodeoxycholic Acid4-cresolAntioxidantsCresolsEndoplasmic Reticulum Chaperone BiPHSPA5 protein, humanPrPC ProteinsReactive Oxygen SpeciesTaurochenodeoxycholic Acidursodoxicoltaurinecellular prion proteinmesenchymal stem cellsP-cresolreactive oxygen speciestauroursodeoxycholic acid

Identifiers

PMID29370069
PMCPMC5855574
OpenAlexW2792522485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.