ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2018
Genetic and Environmental Contributions of Negative Valence Systems to Internalizing Pathways.
Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An epigenome-wide association study of early-onset major depression in monozygotic twins.Translational psychiatry · 2020Pooled it
- Small Extracellular Vesicles in Alcohol Use Disorders: A Scoping Review.Consortium psychiatricum · 2026Review
- Genetic and Environmental Influences on Fear Learning and Generalization.Psychophysiology · 2025Article
- Right frontal cingulate cortex mediates the effect of prenatal complications on youth internalizing behaviors.Molecular psychiatry · 2024Article
- Immune cell markers associated with early life major depressive episodes.Journal of mood and anxiety disorders · 2024Article
- Genetic and environmental influences on alpha amylase stress reactivity and shared genetic covariation with cortisol.Psychoneuroendocrinology · 2024Article
- Large-scale integration of DNA methylation and gene expression array platforms identifies bothEpigenetics · 2022Article
- Pediatric assessment of Research Domain Criteria positive and negative valence systems: Partial genetic mediation of links to problem behaviors.Journal of psychopathology and clinical science · 2022Article
- Network Diffusion Embedding Reveals Transdiagnostic Subnetwork Disruption and Potential Treatment Targets in Internalizing Psychopathologies.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Genetic and environmental influences on cortisol reactivity to a psychosocial stressor in adolescents and young adults.Psychoneuroendocrinology · 2021Article
- DNA methylation associated with postpartum depressive symptoms overlaps findings from a genome-wide association meta-analysis of depression.Clinical epigenetics · 2019Article
- Genetic underpinnings of callous-unemotional traits and emotion recognition in children, adolescents, and emerging adults.Journal of child psychology and psychiatry, and allied disciplines · 2019Article
- A Developmental Twin Study of Emotion Recognition and Its Negative Affective Clinical Correlates.Journal of the American Academy of Child and Adolescent Psychiatry · 2018Article
- Confirmatory factor structure and psychometric properties of the Multidimensional Peer Victimization Scale.Journal of psychopathology and behavioral assessment · 2018Article
- Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization.Behavior genetics · 2018Article
- Resting Heart Rate Variability (HRV) in Adolescents and Young Adults from a Genetically-Informed Perspective.Behavior genetics · 2018Article
- Differential Associations of Distress Tolerance and Anxiety Sensitivity With Adolescent Internalizing Psychopathology.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The genetic and environmental contributions of negative valence systems (NVS) to internalizing pathways study (also referred to as the Adolescent and Young Adult Twin Study) was designed to examine varying constructs of the NVS as they relate to the development of internalizing disorders from a genetically informed perspective. The goal of this study was to evaluate genetic and environmental contributions to potential psychiatric endophenotypes that contribute to internalizing psychopathology by studying adolescent and young adult twins longitudinally over a 2-year period. This report details the sample characteristics, study design, and methodology of this study. The first wave of data collection (i.e., time 1) is complete; the 2-year follow-up (i.e., time 2) is currently underway. A total of 430 twin pairs (N = 860 individual twins; 166 monozygotic pairs; 57.2% female) and 422 parents or legal guardians participated at time 1. Twin participants completed self-report surveys and participated in experimental paradigms to assess processes within the NVS. Additionally, parents completed surveys to report on themselves and their twin children. Findings from this study will help clarify the genetic and environmental influences of the NVS and their association with internalizing risk. The goal of this line of research is to develop methods for early internalizing disorder risk detection.
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