Evidence map›Paper›PMID 29368802›Full record

Trial reportPhysiological reports2018

Dietary nitrate-induced increases in human muscle power: high versus low responders.

Andrew R Coggan, Seth R Broadstreet, Deana Mikhalkova, Indra Bole, Joshua L Leibowitz, Ana Kadkhodayan, Soo Park, Deepak P Thomas, Dakkota Thies, Linda R Peterson

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03513302 (Dietary Nitrate and Muscle Power With Aging), which is not on this map. Cited by 44 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03513302 nacompletednot on this mapstarted 2019, after this paper: background citation

Dietary Nitrate and Muscle Power With Aging

TypeinterventionalSponsorIndiana UniversityRan2019 to 2022Enrolled47ConditionsAging, SarcopeniaArmsplacebo, nitrate
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  3. The Effects of Dietary Nitrate Supplementation on Explosive Exercise Performance: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  9. Dietary nitrate and muscle contractile function in women: effect of menstrual cycle phase.Journal of applied physiology (Bethesda, Md. : 1985) · 2026
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  18. Dose-Response Effect of Dietary Nitrate on Muscle Contractility and Blood Pressure in Older Subjects: A Pilot Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Trial
  19. A Single Dose of Dietary Nitrate Increases Maximal Knee Extensor Angular Velocity and Power in Healthy Older Men and Women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew R CogganDepartments of Kinesiology, Indiana University Purdue University Indianapolis, Indianapolis, Indiana.
Seth R BroadstreetDepartments of Kinesiology, Indiana University Purdue University Indianapolis, Indianapolis, Indiana.
Deana MikhalkovaDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Indra BoleDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Joshua L LeibowitzDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Ana KadkhodayanDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Soo ParkDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Deepak P ThomasDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Dakkota ThiesDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Linda R PetersonDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

Maximal neuromuscular power is an important determinant of athletic performance and also quality of life, independence, and perhaps even mortality in patient populations. We have shown that dietary nitrate (NO

Indexed as

Beta vulgarisAdultAgedAthletic PerformanceCross-Over StudiesDietary SupplementsDouble-Blind MethodFemaleFruit and Vegetable JuicesHumansMaleMiddle AgedMuscle Fibers, SkeletalNitratesNitric OxidePlant RootsNitratesNitric OxideFiber typeisokinetic dynamometrynitric oxidesex differences

Identifiers

PMID29368802
PMCPMC5789728

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.