Evidence map›Paper›PMID 29368690›Full record

ArticleeLife2018

BAD and K

Juan Ramón Martínez-François, María Carmen Fernández-Agüera, Nidhi Nathwani, Carolina Lahmann, Veronica L Burnham, Nika N Danial, Gary Yellen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Calcium-Activated Potassium Channel KMolecular neurobiology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. bioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Electro-metabolic signaling.The Journal of general physiology · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Non-Canonical Roles of Apoptotic Caspases in the Nervous System.Frontiers in cell and developmental biology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Juan Ramón Martínez-FrançoisDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID http://orcid.org/0000-0002-1035-2574
María Carmen Fernández-AgüeraDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.ORCID http://orcid.org/0000-0002-0769-213X
Nidhi NathwaniDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Carolina LahmannDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Veronica L BurnhamDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Nika N DanialDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Gary YellenDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID http://orcid.org/0000-0003-4228-7866
Boston University · USDana-Farber Cancer Institute · US

Funding

Viral ModuleP30EY012196 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ZHIGANG HE · 1998 to 2026
$21.3M
Super-Resolution ImagingP30NS072030 · NINDS · HARVARD MEDICAL SCHOOL · PI REGEHR, WADE G · 2011 to 2020
$5.8M
Single cell analysis of metabolism using genetically-encoded fluorescent sensorsDP1EB016985 · NIBIB · HARVARD MEDICAL SCHOOL · PI YELLEN, GARY I · 2012 to 2016
$4.2M
Cellular mechanisms of dietary therapy for epilepsyR01NS055031 · NINDS · HARVARD MEDICAL SCHOOL · PI YELLEN, GARY I · 2008 to 2016
$3.2M
Mechanisms of seizure resistance in a mouse genetic model with altered metabolismR01NS102586 · NINDS · HARVARD MEDICAL SCHOOL · PI YELLEN, GARY I · 2018 to 2022
$1.9M
Metabolic control of neuronal activity by fuel substrate switchingR01NS083844 · NINDS · DANA-FARBER CANCER INST · PI DANIAL, NIKA N, YELLEN, GARY I · 2013 to 2016
$1.4M
Imaging cellular energy metabolism in vivo using fluorescent biosensorsF32NS093784 · NINDS · HARVARD MEDICAL SCHOOL · PI LAHMANN, CAROLINA · 2015 to 2017
$158k
European Molecular Biology Organization 473-2016NEI NIH HHS P30 EY012196NIBIB NIH HHS DP1 EB016985NIH HHS DP1 EB016985NIH HHS R01 NS055031NIH HHS R01 NS083844NINDS NIH HHS F32 NS093784NINDS NIH HHS P30 NS072030NINDS NIH HHS R01 NS055031NINDS NIH HHS R01 NS083844NINDS NIH HHS R01 NS102586
6 · The paper itself

Abstract

Brain metabolism can profoundly influence neuronal excitability. Mice with genetic deletion or alteration of

Indexed as

Animalsbcl-Associated Death ProteinEntorhinal CortexKATP ChannelsMiceMice, KnockoutNeuronsSeizuresBad protein, mousebcl-Associated Death ProteinKATP ChannelsBrain sliceCalcium imagingEpilepsyMetabolic seizure resistancemouseneuroscience

Identifiers

PMID29368690
PMCPMC5785210
OpenAlexW2784397665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.