Evidence map›Paper›PMID 29368625›Full record

ReviewCritical care (London, England)2018

Perioperative fluid management in kidney transplantation: a black box.

Maria Helena Calixto Fernandes, Thomas Schricker, Sheldon Magder, Roupen Hatzakorzian

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03446196 (Hemodynamic Optimization During Single Kidney Transplantation With MostcareUP), which is not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03446196 nacompletednot on this map

Hemodynamic Optimization During Single Kidney Transplantation With MostcareUP

TypeinterventionalSponsorUniversity of PadovaRan2018 to 2019Enrolled40ConditionsTransplant DysfunctionArmsFluid replacement based on MOSTCARE up
3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  16. Review
  17. Intraoperative blood pressure management during kidney transplantation: Grafts under pressure.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Helena Calixto FernandesDepartment of Anesthesia, Royal Victoria Hospital, 1001 Decarie Blvd, Montreal, QC, H4A 3J1, Canada. mariahelena3@hotmail.com.
Thomas SchrickerDepartment of Anesthesia, Royal Victoria Hospital, 1001 Decarie Blvd, Montreal, QC, H4A 3J1, Canada.
Sheldon MagderDepartment of Critical Care Medicine, Royal Victoria Hospital, 1001 Decarie Blvd, Montreal, QC, H4A 3J1, Canada.
Roupen HatzakorzianDepartment of Anesthesia, Royal Victoria Hospital, 1001 Decarie Blvd, Montreal, QC, H4A 3J1, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of delayed graft function in patients undergoing kidney transplantation remains significant. Optimal fluid therapy has been shown to decrease delayed graft function after renal transplantation. Traditionally, the perioperative volume infusion regimen in this patient population has been guided by central venous pressure as an estimation of the patient's volume status and mean arterial pressure, but this is based on sparse evidence from mostly retrospective observational studies. Excessive volume infusion to the point of no further fluid responsiveness can damage the endothelial glycocalyx and is no longer considered to be the best approach. However, achievement of adequate flow to maintain sufficient tissue perfusion without maximization of cardiac filling remains a challenge. Novel minimally invasive technologies seem to reliably assess volume responsiveness, heart function and perfusion adequacy. Prospective comparative clinical studies are required to better understand the use of dynamic analyses of flow parameters for adequate fluid management in kidney transplant recipients. We review perioperative fluid assessment techniques and discuss conventional and novel monitoring strategies in the kidney transplant recipient.

Indexed as

Blood PressureCentral Venous PressureDelayed Graft FunctionEchocardiography, TransesophagealFluid TherapyHeart RateHumansKidney TransplantationMonitoring, PhysiologicPerioperative CarePulmonary ArteryDelayed graft functionFluid managementFluid responsivenessIntravascular fluid assessmentKidney transplantationPerioperative volume infusion

Identifiers

PMID29368625
PMCPMC5784708

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.