Evidence map›Paper›PMID 29368603›Full record

ArticlePediatric rheumatology online journal2018

Defining the normal appearance of the temporomandibular joints by magnetic resonance imaging with contrast: a comparative study of children with and without juvenile idiopathic arthritis.

Matthew L Stoll, Saurabh Guleria, Melissa L Mannion, Daniel W Young, Stuart A Royal, Randy Q Cron, Yoginder N Vaid

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric rheumatology online journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthew L StollDepartment of Pediatrics, University of Alabama at Birmingham, CPP N G10 / 1600 7th Avenue South, Birmingham, AL, 35233, USA. mstoll@peds.uab.edu.
Saurabh GuleriaDepartment of Radiology at Children's of Alabama, CH 2 FL / 1600 7th Avenue South, Birmingham, AL, 35233, USA.
Melissa L MannionDepartment of Pediatrics, University of Alabama at Birmingham, CPP N G10 / 1600 7th Avenue South, Birmingham, AL, 35233, USA.
Daniel W YoungDepartment of Radiology at Children's of Alabama, CH 2 FL / 1600 7th Avenue South, Birmingham, AL, 35233, USA.
Stuart A RoyalDepartment of Radiology at Children's of Alabama, CH 2 FL / 1600 7th Avenue South, Birmingham, AL, 35233, USA.
Randy Q CronDepartment of Pediatrics, University of Alabama at Birmingham, CPP N G10 / 1600 7th Avenue South, Birmingham, AL, 35233, USA.
Yoginder N VaidDepartment of Radiology at Children's of Alabama, CH 2 FL / 1600 7th Avenue South, Birmingham, AL, 35233, USA.
Children's of Alabama · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUp to 80% of children with juvenile idiopathic arthritis (JIA) develop arthritis involving their temporomandibular joint (TMJ). Recent studies have questioned the sensitivity of an abnormal MRI in the diagnosis of active arthritis.

methods122 children without arthritis undergoing contrast MRI of the head were prospectively consented to undergo a simultaneous contrast MRI of their TMJs. As a comparison point, the initial MRI of the TMJ of 35 newly diagnosed children with JIA were retrospectively scored. The presence and size of effusion and contrast enhancement were measured in the left TMJ in all subjects.

results62/122 (51%) controls compared to only 10/35 JIA (29%) patients had an effusion (p = 0.022). Contrast enhancement was present in ≥97% of both groups, although the size of the enhancement was, on average, 0.2 mm larger in controls (1.1 ± 0.24 vs 0.88 ± 0.27 mm, p <  0.001). Among JIA patients, the size of the enhancement correlated inversely with disease duration (r = - 0.475, p = 0.005). Chronic changes were present in none of the controls versus 2/35 (5.5%) of the JIA patients (p = 0.049).

conclusionFindings consistent with minimally active TMJ arthritis appear to be equally likely in children with JIA as compared to non-inflamed controls, while this and other studies confirm that chronic changes are specific to JIA. Thus, small amounts of effusion or contrast enhancement, in the absence of chronic changes, should be interpreted with caution.

Indexed as

AdolescentArthritis, JuvenileChildChild, PreschoolContrast MediaFemaleHumansInfantMagnetic Resonance ImagingMaleProspective StudiesRetrospective StudiesTemporomandibular JointTemporomandibular Joint DisordersContrast MediaJuvenile idiopathic arthritisMagnetic resonance imagingTemporomandibular joint

Identifiers

PMID29368603
PMCPMC5784616
OpenAlexW2792092864

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.