ArticleThe Journal of physiology2018
A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.
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Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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56citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
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Who cites it
56 citing papers in PubMed, 88 citations in OpenAlex.
- Deficient TRPM3-linked mitochondrial CaBMC immunology · 2026Article
- Activated T cells induce apoptosis in A549 lung adenocarcinoma cells via TRPV4-mediated calcium influx.Scientific reports · 2026Article
- KCa3.1 channels regulate the tumor infiltration of functionally competent NK cells in head and neck cancer.Scientific reports · 2025Article
- Stress granules and cell death: crosstalk and potential therapeutic strategies in infectious diseases.Cell death & disease · 2025Review
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- Presetting CAR-T cells during ex vivo biomanufacturing.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Review
- Imaging BiTE-Mediated Activation of Primary Human CD8Methods in molecular biology (Clifton, N.J.) · 2025Article
- Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.Frontiers in medicine · 2025Article
- Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory study.Frontiers in immunology · 2025Article
- Inhibition of KCancers · 2024Article
- New insights into the stromal interaction molecule 2 function and its impact on the immunomodulation of tumor microenvironment.Cell & bioscience · 2024Review
- Natural Killer Cell Mechanosensing in Solid Tumors.Bioengineering (Basel, Switzerland) · 2024Review
- A solution for highly efficient electroporation of primary cytotoxic T lymphocytes.BMC biotechnology · 2024Article
- Synthetic Biology Meets CaCells · 2024Review
- Activity of Potassium Channels in CD8International journal of molecular sciences · 2024Article
- Application of calcium overload-based ion interference therapy in tumor treatment: strategies, outcomes, and prospects.Frontiers in pharmacology · 2024Review
- Regulatory role of CD39 and CD73 in tumor immunity.Future oncology (London, England) · 2024Review
- Novel characterization of endogenous transient receptor potential melastatin 3 ion channels from Gulf War Illness participants.PloS one · 2024Article
- Enhanced cytotoxic activity of natural killer cells from increased calcium influx induced by electrical stimulation.PloS one · 2024Article
- Apoptotic contraction drives target cell release by cytotoxic T cells.Nature immunology · 2023Article
Corrections and comments
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Authors and funding
25 authors at 3 institutions in 2 countries.
Xiao ZhouBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Kim S FriedmannBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Hélène LyrmannBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Yan ZhouBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Rouven SchoppmeyerBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Arne KnörckBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Sebastian MangBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Cora HoxhaBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Adrian AngenendtBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Christian S BackesBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Carmen MangerichBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Renping ZhaoBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Sabrina CappelloBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Gertrud SchwärBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Carmen HässigBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Marc NeefDepartment of Theoretical Physics, Saarland University, Saarbrücken, 66041, Germany.
Bernd BufePhysiology, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Frank ZufallPhysiology, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Karsten KruseDepartment of Theoretical Physics, Saarland University, Saarbrücken, 66041, Germany.
Barbara A NiemeyerMolecular Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Annette LisBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Bin QuBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Carsten KummerowBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.
Eva C SchwarzBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.ORCID 0000-0002-6503-4864
Markus HothBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421, Germany.ORCID 0000-0001-7080-4643
Saarland University · DEUniversity of Geneva · CHUniversity of Göttingen · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
key pointsCytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are required to eliminate cancer cells. We analysed the Ca ABSTRACT: Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are required to protect the human body against cancer. Ca
Indexed as
ApoptosisCell ProliferationCalciumCell MovementCytoplasmic GranulesHumansKiller Cells, NaturalNeoplasmsPerforinT-Lymphocytes, CytotoxicTumor Cells, CulturedCalciumPerforincancer cellscytotoxic immune cellskilling efficiency
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.