Evidence map›Paper›PMID 29368299›Full record

ArticleJournal of cell communication and signaling2018

Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation.

Lu Li, Linlin Jing, Junjiang Wang, Wenjuan Xu, Xianling Gong, Yiye Zhao, Ye Ma, Xueqing Yao, Xuegang Sun

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell communication and signaling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Lu LiSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Linlin JingTCM Integrated Hospital of Southern Medical University, Guangzhou, 510315, China.
Junjiang WangDepartment of Gastrointestinal Surgery, Guangdong General Hospital, Guangzhou, 510120, China.
Wenjuan XuSchool of Traditional Chinese Medicine, Binzhou Medical University, Yantai, Shandong, 256600, China.
Xianling GongSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Yiye ZhaoTCM Integrated Hospital of Southern Medical University, Guangzhou, 510315, China.
Ye MaSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Xueqing YaoDepartment of Gastrointestinal Surgery, Guangdong General Hospital, Guangzhou, 510120, China.
Xuegang SunSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. sxg_smu@126.com.ORCID http://orcid.org/0000-0001-6581-0520
TCM-Intigrated Cancer Center of Southern Medical University · CNGuangdong General Hospital · CNSouthern Medical University · CNBinzhou Medical University · CNGuangdong Medical College · CN

Funding

Guangdong Province Bureau of Traditional Chinese Medicine Scientific Research Project 20151024, 20161161National Science Foundation of China 81573848Natural Science Foundation of Guangdong Province 2014A030313323Planned Science Technology Project of Guangzhou 201607010146
6 · The paper itself

Abstract

Colorectal cancer is generally believed to progress through an adenoma - carcinoma sequence. Adenomatous polyposis coli (APC) mutations serve as the initiating event in adenoma formation. The Apc

Indexed as

AcetylationAdenomaAtractylenolide IAutophagyD-dopachrome tautomerasep53Sirt 1

Identifiers

PMID29368299
PMCPMC6235779
OpenAlexW2793941053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.