Evidence map›Paper›PMID 29368194›Full record

ArticleEuropean journal of epidemiology2018

The impact of parity on life course blood pressure trajectories: the HUNT study in Norway.

Eirin B Haug, Julie Horn, Amanda Rose Markovitz, Abigail Fraser, Corrie Macdonald-Wallis, Kate Tilling, Pål Richard Romundstad, Janet Wilson Rich-Edwards, Bjørn Olav Åsvold

Erratum issuedAbstract read
In one paragraph

Article in European journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  8. Placental syndromes and maternal cardiovascular health.Clinical science (London, England : 1979) · 2023
    Review
  9. Placental syndromes and long-term risk of hypertension.Journal of human hypertension · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Blood pressure and adiposity in midlife Singaporean women.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Eirin B HaugDepartment of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Postboks 8905, 7491, Trondheim, Norway. eirin.haug@ntnu.no.ORCID http://orcid.org/0000-0001-8565-9151
Julie HornDepartment of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Postboks 8905, 7491, Trondheim, Norway.
Amanda Rose MarkovitzThe Harvard T.H Chan School of Public Health, Harvard University, Boston, MA, USA.
Abigail FraserMRC Integrative Epidemiology Unit and Population Health Sciences, University of Bristol, Bristol, UK.
Corrie Macdonald-WallisMRC Integrative Epidemiology Unit and Population Health Sciences, University of Bristol, Bristol, UK.
Kate TillingMRC Integrative Epidemiology Unit and Population Health Sciences, University of Bristol, Bristol, UK.
Pål Richard RomundstadDepartment of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Postboks 8905, 7491, Trondheim, Norway.
Janet Wilson Rich-EdwardsThe Harvard T.H Chan School of Public Health, Harvard University, Boston, MA, USA.
Bjørn Olav ÅsvoldDepartment of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Postboks 8905, 7491, Trondheim, Norway.

Funding

American Heart Association (US) 16PRE29690006Medical Research Council MC_UU_12013/5Medical Research Council MR/M009351/1Medical Research Council (GB) MR/M009351/1Norges Forskningsråd 231149/F20Norges Forskningsråd (NO) 231149/F20
6 · The paper itself

Abstract

The drop in blood pressure during pregnancy may persist postpartum, but the impact of pregnancy on blood pressure across the life course is not known. In this study we examined blood pressure trajectories for women in the years preceding and following pregnancy and compared life course trajectories of blood pressure for parous and nulliparous women. We linked information on all women who participated in the population-based, longitudinal HUNT Study, Norway with pregnancy information from the Medical Birth Registry of Norway. A total of 23,438 women were included with up to 3 blood pressure measurements per woman. Blood pressure trajectories were compared using a mixed effects linear spline model. Before first pregnancy, women who later gave birth had similar mean blood pressure to women who never gave birth. Women who delivered experienced a drop after their first birth of - 3.32 mmHg (95% CI, - 3.93, - 2.71) and - 1.98 mmHg (95% CI, - 2.43, - 1.53) in systolic and diastolic blood pressure, respectively. Subsequent pregnancies were associated with smaller reductions. These pregnancy-related reductions in blood pressure led to persistent differences in mean blood pressure, and at age 50, parous women still had lower systolic (- 1.93 mmHg; 95% CI, - 3.33, - 0.53) and diastolic (- 1.36 mmHg; 95% CI, - 2.26, - 0.46) blood pressure compared to nulliparous women. The findings suggest that the first pregnancy and, to a lesser extent, successive pregnancies are associated with lasting and clinically relevant reductions in systolic and diastolic blood pressure.

Indexed as

AdultAgedAge FactorsBlood PressureFemaleHumansLongitudinal StudiesMiddle AgedNorwayParityPregnancyRegistriesYoung AdultBlood pressureEpidemiologyLife courseParityPregnancy

Identifiers

PMID29368194
PMCPMC6061132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.