Evidence map›Paper›PMID 29368038›Full record

ArticleParasitology research2018

Green drugs in the fight against Anisakis simplex-larvicidal activity and acetylcholinesterase inhibition of Origanum compactum essential oil.

Víctor López, María Cascella, Giovanni Benelli, Filippo Maggi, Carlota Gómez-Rincón

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 63 citations in OpenAlex.

  1. Food and waterborne parasitology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Essential Oils as Novel Anthelmintic Drug Candidates.Molecules (Basel, Switzerland) · 2022
    Review
  8. Article
  9. Studies on the Phytochemical Profile ofInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Action of Carvacrol onPharmaceuticals (Basel, Switzerland) · 2021
    Article
  12. Anti-protozoal activity of Thymol and a Thymol ester against Cryptosporidium parvum in cell culture.International journal for parasitology. Drugs and drug resistance · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Efficacy ofMolecules (Basel, Switzerland) · 2019
    Article
  18. Article
  19. Exploring the Insecticidal Potential of Boldo (Molecules (Basel, Switzerland) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Víctor LópezDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego, 50830, Zaragoza, Spain. ilopez@usj.es.
María CascellaDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego, 50830, Zaragoza, Spain.
Giovanni BenelliDepartment of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, 56124, Pisa, Italy. benelli.giovanni@gmail.com.
Filippo MaggiSchool of Pharmacy, University of Camerino, Camerino, Italy.
Carlota Gómez-RincónDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego, 50830, Zaragoza, Spain.
Universidad San Jorge · ESUniversità di Camerino · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anisakiasis is a fish-borne parasitic disease caused by the consumption of raw or undercooked fish, as well as cephalopods, contaminated by third instar larvae (L3) of species belonging to the genus Anisakis (Anisakidae). Origanum compactum is a small herbaceous aromatic plant endemic to Spain and Morocco. In Morocco, the plant is used under infusion to treat heart diseases and intestinal pains or as preservative for foodstuffs. This is the first time that the O. compactum essential oil is tested against the parasitic nematode Anisakis simplex. The phytochemical analysis by GC-MS revealed carvacrol (50.3%) and thymol (14.8%) as the major oil constituents. The essential oil and its major constituents carvacrol and thymol were tested against A. simplex L3 larvae isolated from blue whiting fish (Micromesistius poutassou). A. simplex mortality (%) after 24 and 48 h of treatment at 1 μl/ml was 100%, with a low LD

Indexed as

AnimalsAnisakiasisAnisakisAnthelminticsCholinesterase InhibitorsCymenesFish DiseasesFishesGas Chromatography-Mass SpectrometryLarvaMonoterpenesOils, VolatileOriganumPlant OilsSpainThymolAnthelminticscarvacrolCholinesterase InhibitorsCymenesMonoterpenesOils, VolatilePlant OilsThymolAnisakisAnthelminticCarvacrolNematodeThymolWaterborne parasitology

Identifiers

PMID29368038
PMCPMC5876267
OpenAlexW2783485845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.