ArticleSleep and biological rhythms
Physiological and autonomic stress responses after prolonged sleep restriction and subsequent recovery sleep in healthy young men.
Article in Sleep and biological rhythms. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Effects of sleep deprivation on heart rate variability: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Effects of Experimental Sleep Restriction on Ambulatory and Sleep Blood Pressure in Healthy Young Adults: A Randomized Crossover Study.Hypertension (Dallas, Tex. : 1979) · 2021Trial
- Cardiac event-induced PTSD symptoms and continuous heart rate in coronary artery disease patients.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- [Joint predictive effect of systolic blood pressure variability and sleep patterns on stroke].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Sleep and circadian rhythms in cardiovascular resilience: mechanisms, implications, and a Roadmap for research and interventions.Nature reviews. Cardiology · 2026Review
- Sleep characteristics and risk factors in patients of insomnia comorbid with anxiety.BMC psychology · 2026Article
- Habitual sleep duration and QT variability index: Correlates of ventricular repolarization lability and all-cause mortality.Heart rhythm · 2026Article
- Sleep structure and autonomic nervous system state during four months of isolation in a space analogue mission.Frontiers in human neuroscience · 2026Article
- The new science of sleep: From cells to large-scale societies.PLoS biology · 2024Article
- A single night of moderate at-home sleep restriction increases hunger and food intake in overweight young adults.Nutrition (Burbank, Los Angeles County, Calif.) · 2023Article
- Non-linear relationship between sleep duration and blood pressure in children with short stature.Frontiers in pediatrics · 2023Article
- Mild to Moderate Sleep Restriction Does Not Affect the Cortisol Awakening Response in Healthy Adult Males.Clocks & sleep · 2022Article
- Effects of sleep deprivation and 4-7-8 breathing control on heart rate variability, blood pressure, blood glucose, and endothelial function in healthy young adults.Physiological reports · 2022Article
- Strategies to Limit Cognitive Impairments under Sleep Restriction: Relationship to Stress Biomarkers.Brain sciences · 2022Article
- Effects of Acute Partial Sleep Deprivation and High-Intensity Interval Exercise on Postprandial Network Interactions.Frontiers in network physiology · 2022Article
- The links between sleep duration, obesity and type 2 diabetes mellitus.The Journal of endocrinology · 2021Review
- Effects of sleep deprivation on sarcopenia and obesity: A narrative review of randomized controlled and crossover trials.Journal of frailty, sarcopenia and falls · 2021Article
- Sleep Extension: A Potential Target for Obesity Treatment.Current diabetes reports · 2020Review
- Sleep duration and blood pressure in children: Analysis of the pan-European IDEFICS cohort.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep.Current biology : CB · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSleep restriction is increasingly common and associated with the development of health problems. We investigated how the neuroendocrine stress systems respond to prolonged sleep restriction and subsequent recovery sleep in healthy young men.
methodsAfter two baseline (BL) nights of 8 h time in bed (TIB), TIB was restricted to 4 h per night for five nights (sleep restriction, SR,
resultsIn the control group, none of the parameters changed. In the experimental group, heart rate increased from 60 ± 1.8 beats per minute (bpm) at BL, to 63 ± 1.1 bpm after SR and further to 65 ± 1.8 bpm after REC. In addition, whole day low-frequency to-high frequency (LF/HF) power ratio of heart rate variability increased from 4.6 ± 0.4 at BL to 6.0 ± 0.6 after SR. Other parameters, including salivary NPY and cortisol levels, remained unaffected.
conclusionsIncreased heart rate and LF/HF power ratio are early signs of an increased sympathetic activity after prolonged sleep restriction. To reliably interpret the clinical significance of these early signs of physiological stress, a follow-up study would be needed to evaluate if the stress responses escalate and lead to more unfavourable reactions, such as elevated blood pressure and a subsequent elevated risk for cardiovascular health problems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.