ArticleScientific reports2018
A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Genetic susceptibility to caffeine intake and metabolism: a systematic review.Journal of translational medicine · 2024Pooled it
- Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis.Journal of human genetics · 2020Pooled it
- GWAS of habitual coffee consumption reveals a sex difference in the genetic effect of the 12q24 locus in the Japanese population.BMC genetics · 2019Pooled it
- Coffee consumption and liver cancer risk in Japan: a meta-analysis of six prospective cohort studies.Nagoya journal of medical science · 2019Pooled it
- Coffee intake, genetic variants, and chronic kidney disease: a cross-sectional analysis of the Japan Multi-Institutional Collaborative Cohort (J-MICC) study.European journal of nutrition · 2025Article
- Relationship between HECTD4 gene variants, obesity, and coffee consumption.European journal of clinical nutrition · 2025Article
- Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Genome-wide analysis and identification of Carotenoid Cleavage Oxygenase (CCO) gene family in coffee (coffee arabica) under abiotic stress.BMC genomic data · 2024Article
- Article
- A genome-wide association study on adherence to low-carbohydrate diets in Japanese.European journal of clinical nutrition · 2022Article
- ALDH2 variance in disease and populations.Disease models & mechanisms · 2022Article
- Genetic determinants of liking and intake of coffee and other bitter foods and beverages.Scientific reports · 2021Article
- Study Profile of the Japan Multi-institutional Collaborative Cohort (J-MICC) Study.Journal of epidemiology · 2021Article
- Article
- A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern.European journal of clinical nutrition · 2021Article
- A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study.Journal of nutritional science · 2021Article
- Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus.Journal of the American Heart Association · 2020Observational
- A Genome-Wide Association Study Identifies the Association between the 12q24 Locus and Black Tea Consumption in Japanese Populations.Nutrients · 2020Article
- Interactions of Habitual Coffee Consumption by Genetic Polymorphisms with the Risk of Prediabetes and Type 2 Diabetes Combined.Nutrients · 2020Article
- GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits.Nature human behaviour · 2020Article
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Authors and funding
36 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coffee is one of the most widely consumed beverages worldwide, and its role in human health has received much attention. Although genome-wide association studies (GWASs) have investigated genetic variants associated with coffee consumption in European populations, no such study has yet been conducted in an Asian population. Here, we conducted a GWAS to identify common genetic variations that affected coffee consumption in a Japanese population of 11,261 participants recruited as a part of the Japan Multi-Institutional Collaborative Cohort (J-MICC) study. Coffee consumption was collected using a self-administered questionnaire, and converted from categories to cups/day. In the discovery stage (n = 6,312), we found 2 independent loci (12q24.12-13 and 5q33.3) that met suggestive significance (P < 1 × 10
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