Evidence map›Paper›PMID 29367537›Full record

ReviewJournal of cardiovascular development and disease2017

Lineages of the Cardiac Conduction System.

Rajiv Mohan, Bas J Boukens, Vincent M Christoffels

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rajiv MohanDepartment of Medical Biology, University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands. r.a.mohan@amc.uva.nl.
Bas J BoukensDepartment of Medical Biology, University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands. b.j.d.boukens@amc.uva.nl.
Vincent M ChristoffelsDepartment of Medical Biology, University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands. v.m.christoffels@amc.uva.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiac conduction system (CCS) initiates and coordinately propagates the electrical impulse to orchestrate the heartbeat. It consists of a set of interconnected components with shared properties. A better understanding of the origin and specification of CCS lineages has allowed us to better comprehend the etiology of CCS disease and has provided leads for development of therapies. A variety of technologies and approaches have been used to investigate CCS lineages, which will be summarized in this review. The findings imply that there is not a single CCS lineage. In contrast, early cell fate decisions segregate the lineages of the CCS components while they remain connected to each other.

Indexed as

cardiac conduction systemcardiac conduction system lineagecardiac developmentcell lineagegenetic fate mapgenetic inducible fate maplineage tracing

Identifiers

PMID29367537
PMCPMC5715704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.