ArticleBMJ case reports2018
Case of acute mixed liver injury due to hypothyroidism.
Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Renal dysfunction caused by severe hypothyroidism diagnosed by renal biopsy: a case report.CEN case reports · 2024Article
- Vitamin D alleviates hypothyroidism associated liver dysfunction: Histological and biochemical evidence.Heliyon · 2023Article
- Biochemical changes in patients during hypothyroid phase after thyroidectomy.Journal of medicine and life · 2022Article
- Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis.Case reports in veterinary medicine · 2021Article
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Authors and funding
3 authors.
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Abstract
The effects of hypothyroidism on the liver are not well understood. A 77-year-old woman with Hashimoto's thyroiditis had stopped taking levothyroxine on her own for 6 months. Her thyroid stimulating hormone (TSH) level was consistent with severe hypothyroidism. She resumed thyroid replacement therapy. The following month, her liver function tests were significantly elevated. Seven weeks after resumption of therapy, her TSH and liver tests had returned to normal. We attribute the mixed hepatocellular injury to hypothyroidism that resolved on correction of the hypothyroid state. This case reminds us that thyroid disease should be considered when evaluating acute liver injury.
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