Evidence map›Paper›PMID 29366967›Full record

ArticleInternational journal for parasitology. Drugs and drug resistance2018

Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum.

Melanie Abongwa, Djordje S Marjanovic, James G Tipton, Fudan Zheng, Richard J Martin, Sasa M Trailovic, Alan P Robertson

Open access · goldAbstract read
In one paragraph

Article in International journal for parasitology. Drugs and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. β-alanine betaine and nAChRs inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Melanie AbongwaDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Djordje S MarjanovicDepartment of Pharmacology and Toxicology, College of Veterinary Medicine, University of Belgrade, Belgrade, Serbia.
James G TiptonDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Fudan ZhengDepartment of Chemistry, College of Liberal Arts and Sciences, Iowa State University, Ames, IA 50011, USA.
Richard J MartinDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Sasa M TrailovicDepartment of Pharmacology and Toxicology, College of Veterinary Medicine, University of Belgrade, Belgrade, Serbia.
Alan P RobertsonDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA. Electronic address: alanr@iastate.edu.
Iowa State University · USUniversity of Belgrade · RS

Funding

RESISTANCE &MODULATION OF LEVAMISOLE RECEPTOR CHANNELSR01AI047194 · NIAID · IOWA STATE UNIVERSITY · PI MARTIN, RICHARD JOHN · 2001 to 2021
$5.8M
Cholinergic receptors on the nematode pharynx: an unexploited drug targetR21AI092185 · NIAID · IOWA STATE UNIVERSITY · PI ROBERTSON, ALAN P · 2011 to 2012
$415k
Eating worms: an unusual nicotinic acetylcholine receptor from the nematode pharynx as a potential drug targetR21AI121831 · NIAID · IOWA STATE UNIVERSITY · PI ROBERTSON, ALAN P · 2016 to 2017
$393k
Summer Research Training for Veterinary Medical StudentsT35OD012199 · OD · IOWA STATE UNIVERSITY · PI MILLER, CATHY L · 2013 to 2017
$153k
NIAID NIH HHS R01 AI047194NIAID NIH HHS R21 AI092185NIAID NIH HHS R21 AI121831NIH HHS T35 OD012199
6 · The paper itself

Abstract

Zolvix

Indexed as

AcetylcholineAminoacetonitrileAnimalsAnthelminticsAscaris suumElectrophysiologyMusclesNicotinic AntagonistsOesophagostomumOocytesReceptors, NicotinicXenopus laevisAcetylcholineAminoacetonitrileAnthelminticsmonepantelNicotinic AntagonistsReceptors, NicotinicMode of actionMonepantelNicotinic acetylcholine receptorsNon-competitive antagonistZolvix(®)

Identifiers

PMID29366967
PMCPMC5963102
OpenAlexW2774517481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.