ArticleAmerican journal of epidemiology2018
Type of Menopause, Age at Menopause, and Risk of Developing Obstructive Sleep Apnea in Postmenopausal Women.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 120 citations in OpenAlex.
- Sleep Disruption in the Menopausal Transition and Postmenopause: A Narrative Review.Obstetrics and gynecology · 2026Review
- Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats.Experimental physiology · 2026Article
- Midlife Sleep and Circadian Health: Implications for Cardiovascular and Cognitive Outcomes.Obstetrics and gynecology clinics of North America · 2026Review
- Menopause and neurological disorders: a roadmap for research.Nature reviews. Neurology · 2026Review
- Arterial Stiffness in Patients with Obstructive Sleep Apnea and Hypertension: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Neurologic Complications of Pregnancy and Menopause.Continuum (Minneapolis, Minn.) · 2026Review
- Polysomnographic characteristics of excessive daytime sleepiness in postmenopausal women with obstructive sleep apnea.Frontiers in sleep · 2026Article
- Approach to obstructive sleep apnea: Interdisciplinary considerations for optimal management.Canadian family physician Medecin de famille canadien · 2026Review
- Evaluation of SIRT1 Protein Levels and SIRT1/rs7895833 Distributions in Turkish Patients With Obstructive Sleep Apnea.Journal of clinical laboratory analysis · 2025Article
- The sleep quality in women with surgical menopause compared to natural menopause based on Ardakan Cohort Study on Aging (ACSA).BMC women's health · 2025Article
- Association Between Obstructive Sleep Apnea and Hearing Loss Using 2019-2021 Korea National Health and Nutrition Examination Survey Data.The journal of international advanced otology · 2025Article
- Menopause and obstructive sleep apnea: revealing an independent mediating role of visceral fat beyond body mass index.BMC endocrine disorders · 2025Article
- Causal Associations Between Obstructive Sleep Apnea and Hypertension: Evidence From a Bidirectional and Multivariable Mendelian Randomization Analysis.International journal of hypertension · 2025Article
- The Recurrence of Venous Thromboembolism in Obstructive Sleep Apnea: A Narrative Review.Canadian respiratory journal · 2025Review
- Association between sleep quality, sleep duration, and physical frailty among adults aged 50 years and older in India.BMC public health · 2024Article
- Association between Healthy Eating Index-2015 total and component food scores with reproductive lifespan among postmenopausal women: a population-based study from NHANES 2005-2016.BMC public health · 2024Article
- Gender differences in obstructive sleep apnea syndrome: a pilot study.Sleep & breathing = Schlaf & Atmung · 2024Article
- Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes.Current cardiology reports · 2024Review
- A Systematic Review of Risk factors for Sleep Apnea.Preventive medicine reports · 2024Review
- Metabolomic profiles of sleep-disordered breathing are associated with hypertension and diabetes mellitus development.Nature communications · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Despite established sex differences and longstanding hypotheses of sex hormone influence in the etiology of obstructive sleep apnea (OSA), we have found no studies that evaluated type of menopause and age at menopause, which affect postmenopausal hormonal milieu, in relation to OSA risk in women. We followed 50,473 postmenopausal women from the Nurses' Health Study during 2002-2012 and 53,827 postmenopausal women from the Nurses' Health Study II during 1995-2013, with 1,712 and 2,560 incident OSA diagnoses, respectively. Compared with natural menopause, the pooled hazard ratio for OSA was 1.27 (95% confidence interval (CI): 1.17, 1.38) for surgical menopause by hysterectomy/oophorectomy. The association remained the same after further accounting for age at menopause (hazard ratio = 1.26, 95% CI: 1.15, 1.38). The risk associated with surgical menopause was higher among women who were not obese as well as among women who never used hormone therapy (P for interaction < 0.05). Earlier menopause was associated with higher OSA risk prior to adjustment for type of menopause (comparing those aged <40 years versus those aged 50-54 years, hazard ratio = 1.21, 95% CI: 1.08, 1.35; P for trend = 0.008), although no association was observed after the adjustment. Surgical as compared with natural menopause was independently associated with higher OSA risk in postmenopausal women. Our results provide additional evidence for a role for sex hormones, particularly abrupt hormonal changes, in modulating OSA risk.
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