Evidence map›Paper›PMID 29365005›Full record

ReviewJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

Recommendations for the pharmacological treatment of COPD: questions and answers.

Frederico Leon Arrabal Fernandes, Alberto Cukier, Aquiles Assunção Camelier, Carlos Cezar Fritscher, Cláudia Henrique da Costa, Eanes Delgado Barros Pereira, Irma Godoy, José Eduardo Delfini Cançado, José Gustavo Romaldini, Jose Miguel Chatkin and 14 more

Open access · diamondAbstract readReview
In one paragraph

Review in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 52 citations in OpenAlex.

  1. Severity of COPD in comparison with acute myocardial infarction: evidence of in-hospital mortality in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. November 18: World COPD Day 2020. Is it a date to celebrate?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021
    Article
  6. Article
  7. COPD: more treatment will translate to better breathing. Will it?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019
    Article
  8. Jornal Brasileiro de Pneumologia and Sociedade Brasileira de Pneumologia e Tisiologia: perspectives for the next four years.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019
    Article
  9. The need for a balance between highly prevalent diseases and neglected diseases.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
  10. Exploratory analysis of requests for authorization to dispense high-cost medication to COPD patients: the São Paulo "protocol".Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
  11. Drug target insights
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 18 institutions in 2 countries.

Frederico Leon Arrabal Fernandes. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.
Alberto Cukier. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.
Aquiles Assunção Camelier. Universidade do Estado da Bahia - UNEB - Salvador (BA) Brasil.
Carlos Cezar Fritscher. Faculdade de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS- Porto Alegre (RS)Brasil.
Cláudia Henrique da Costa. Universidade Estadual do Rio de Janeiro, Rio de Janeiro (RJ) Brasil.
Eanes Delgado Barros Pereira. Universidade Federal do Ceará, Fortaleza (CE) Brasil.
Irma Godoy. Departamento de Medicina Interna, Área de Pneumologia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista - UNESP - Botucatu (SP) Brasil.
José Eduardo Delfini Cançado. Faculdade de Ciências Médicas, Santa Casa de Misericórdia de São Paulo,São Paulo (SP) Brasil.
José Gustavo Romaldini. Faculdade de Ciências Médicas, Santa Casa de Misericórdia de São Paulo,São Paulo (SP) Brasil.
Jose Miguel Chatkin. Faculdade de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS- Porto Alegre (RS)Brasil.
José Roberto Jardim. Faculdade de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo (SP) Brasil.
Marcelo Fouad Rabahi. Faculdade de Medicina, Universidade Federal de Goiás, Goiânia (GO) Brasil.
Maria Cecília Nieves Maiorano de Nucci. AC Camargo Cancer Center, São Paulo (SP) Brasil.
Maria da Penha Uchoa Sales. Hospital de Messejana Dr Carlos Alberto Studart Gomes, Fortaleza (CE) Brasil.
Maria Vera Cruz de Oliveira Castellano. Serviço de Pneumologia, Hospital do Servidor Público Estadual de São Paulo, São Paulo (SP) Brasil.
Miguel Abidon Aidé. Faculdade de Medicina, Universidade Federal Fluminense, Niterói (RJ) Brasil.
Paulo José Zimermann Teixeira. Departamento de Clínica Médica, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre (RS) Brasil.
Renato Maciel. Disciplina de Pneumologia, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte (MG) Brasil.
Ricardo de Amorim Corrêa. Faculdade de Medicina, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte (MG) Brasil.
Roberto Stirbulov. Faculdade de Ciências Médicas, Santa Casa de Misericórdia de São Paulo,São Paulo (SP) Brasil.
Rodrigo Abensur Athanazio. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.
Rodrigo Russo. Departamento de Medicina, Universidade Federal de São João Del Rei - UFSJ - São João Del Rei (MG) Brasil.
Suzana Tanni Minamoto. Departamento de Medicina Interna, Área de Pneumologia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista - UNESP - Botucatu (SP) Brasil.
Fernando Luiz Cavalcanti Lundgren. Hospital Otavio de Freitas, Recife (PE), Brasil.
Irmandade da Santa Casa de Misericórdia de São Paulo · BRUniversidade de São Paulo · BRPontifícia Universidade Católica do Rio Grande do Sul · BRUniversidade Estadual Paulista (Unesp) · BRAC Camargo Hospital · BREscola Bahiana de Medicina e Saúde Pública · BRFaculdade de Ciências Médicas de Minas Gerais · BRFederal University of São João del-Rei · BRHospital de Messejana · BRHospital do Servidor Público Estadual · BRSt Olav's University Hospital · NOUniversidade do Estado do Rio de Janeiro · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal de Goiás · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Ceará · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of COPD has become increasingly effective. Measures that range from behavioral changes, reduction in exposure to risk factors, education about the disease and its course, rehabilitation, oxygen therapy, management of comorbidities, and surgical and pharmacological treatments to end-of-life care allow health professionals to provide a personalized and effective therapy. The pharmacological treatment of COPD is one of the cornerstones of COPD management, and there have been many advances in this area in recent years. Given the greater availability of drugs and therapeutic combinations, it has become increasingly challenging to know the indications for, limitations of, and potential risks and benefits of each treatment modality. In order to critically evaluate recent evidence and systematize the major questions regarding the pharmacological treatment of COPD, 24 specialists from all over Brazil gathered to develop the present recommendations. A visual guide was developed for the classification and treatment of COPD, both of which were adapted to fit the situation in Brazil. Ten questions were selected on the basis of their relevance in clinical practice. They address the classification, definitions, treatment, and evidence available for each drug or drug combination. Each question was answered by two specialists, and then the answers were consolidated in two phases: review and consensus by all participants. The questions answered are practical questions and help select from among the many options the best treatment for each patient and his/her peculiarities.

Indexed as

Disease ManagementHumansPulmonary Disease, Chronic ObstructiveSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID29365005
PMCPMC5687967
OpenAlexW2754844492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.