ArticlePloS one2018
Physical multimorbidity and loneliness: A population-based study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05264207 (Nursing Students' Visits to Older Adults With Multiple Chronic Conditions), which is not on this map. Cited by 59 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nursing Students' Visits to Older Adults With Multiple Chronic Conditions: Effects on Self-care and Other Related Variables (VISITAME)
Who cites it
59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Relationship between severe mental illness and physical multimorbidity: a meta-analysis and call for action.BMJ mental health · 2023Pooled it
- Peer support for people with chronic conditions: a systematic review of reviews.BMC health services research · 2022Pooled it
- Multimorbidity, Loneliness, and Social Isolation. A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Social Support and Social Strain Sources as Predictors of Multimorbidity Changes in Middle-Aged and Older Adults.Journal of aging and health · 2026Article
- Loneliness and Mental Health Distress among University Students and Staff in Trinidad and Tobago: A Cross-Sectional Survey.Journal of racial and ethnic health disparities · 2026Article
- Suicidal ideation and its determinants among Palestinian university students.Scientific reports · 2026Article
- Health vulnerability and loneliness among adolescent and young adult populations: a comparison of generations based on a nationwide survey in Japan.BMJ public health · 2026Article
- Potential Risk Factors for Lonely Death: A Nationwide Case-Control Study in Korea.Journal of Korean medical science · 2025Article
- The Mediating Role of Self-Esteem in the Relationship Between Loneliness and Phubbing: Evidence from a Cross-Sectional Study.Journal of clinical medicine · 2025Article
- The joint effects of loneliness and interpersonal abuse on suicidal thoughts and behaviors among young adults in higher education in the United States.BMC psychology · 2025Article
- Promoting physical activity among community-dwelling seniors living in a Francophone rural area in New Brunswick: a pre-implementation qualitative study.Frontiers in public health · 2025Article
- Increased social differences, loneliness, and sleep deprivation among undergraduate nursing students in Norway, when writing their bachelor's thesis during the COVID-19 pandemic. A qualitative study.SAGE open medicine · 2025Article
- Article
- Essential New Complexity-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and Multilevel Phenomenology.Journal of clinical medicine · 2024Review
- Loneliness and low fruit and vegetable consumption among adults in Japan.Frontiers in public health · 2024Article
- Multimorbidity and health-related quality of life amongst Indigenous Australians: A longitudinal analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Exploring illness perceptions of multimorbidity among community-dwelling older adults: a mixed methods study.Aging and health research · 2023Article
- Effects of home visiting programmes on community-dwelling older adults with chronic multimorbidity: a scoping review.BMC nursing · 2023Article
- An Assessment of Patient Portal Messaging Use by Patients With Multiple Chronic Conditions Living in Rural Communities: Retrospective Analysis.Journal of medical Internet research · 2023Article
- The prevalence of chronic and episodic loneliness and social isolation from a longitudinal survey.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multimorbidity has been linked to a variety of negative outcomes although as yet, there has been little research on its association with loneliness. This study examined the association between physical multimorbidity (≥ 2 physical diseases) and loneliness in the general population and its potential mediators. Data came from the Adult Psychiatric Morbidity Survey 2007 (N = 7403, aged ≥16 years). Information was obtained on 20 doctor diagnosed physical conditions that were present in the previous year. An item from the Social Functioning Questionnaire (SFQ) was used to obtain information on loneliness. Multivariable logistic regression analysis was used to examine associations. An increasing number of physical diseases was associated with higher odds for loneliness. Compared to no physical diseases, the odds ratio (OR) (95% confidence interval: CI) for loneliness increased from 1.34 (1.13-1.59) to 2.82 (2.11-3.78) between one and ≥5 physical diseases. This association was particularly strong in the youngest age group (i.e. 16-44 years). The loneliness-physical multimorbidity association was significantly mediated by stressful life events (% mediated 11.1%-30.5%), anxiety (30.2%), and depression (15.4%). Physical multimorbidity is associated with increased odds for loneliness. Prospective research is now needed to further elucidate this association and the factors that underlie it.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.