Evidence map›Paper›PMID 29364839›Full record

ArticleBiomolecules2018

The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity.

Steven G Biesecker, Lauren K Nicastro, R Paul Wilson, Çağla Tükel

Abstract read
In one paragraph

Article in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. The Evolution of Functional Amyloids and Their Impact on Host-Microbe Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Staphylococcus epidermidis biofilm assembly and self-dispersion: bacteria and matrix dynamics.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  7. Review
  8. Amyloid Fibrils Produced byInternational journal of molecular sciences · 2023
    Article
  9. Article
  10. Invasive Non-TyphoidalInfection and immunity · 2023
    Article
  11. Susceptibility and Virulence ofMicroorganisms · 2023
    Article
  12. Review
  13. Amyloid-containing biofilms and autoimmunity.Current opinion in structural biology · 2022
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven G BieseckerDepartment of Microbiology and Immunology, School of Medicine, Temple University, Philadelphia, PA 19140, USA. biesecker.steven@gmail.com.
Lauren K NicastroDepartment of Microbiology and Immunology, School of Medicine, Temple University, Philadelphia, PA 19140, USA. tug03848@temple.edu.
R Paul WilsonDepartment of Microbiology and Immunology, School of Medicine, Temple University, Philadelphia, PA 19140, USA. rpwilsonphd@gmail.com.
Çağla TükelDepartment of Microbiology and Immunology, School of Medicine, Temple University, Philadelphia, PA 19140, USA. ctukel@temple.edu.ORCID 0000-0001-7073-0226

Funding

Inflammasome activation by Salmonella typhimurium biofilmsR21AI126133 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI TUKEL, CAGLA · 2016 to 2017
$429k
Immune recognition of amyloid/extracellular DNA complexesR21AI132996 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI TUKEL, CAGLA · 2017 to 2018
$429k
The role of curli fibrils in modulating immune responses in the gutR21AI105370 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI TUKEL, CAGLA · 2014 to 2015
$428k
NIAID NIH HHS R21 AI105370NIAID NIH HHS R21 AI126133NIAID NIH HHS R21 AI132996
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacteremiaBacterial ProteinsComplement ActivationComplement C1qComplement C3bEscherichia coliFemaleHumansMiceMice, Inbred C57BLProtein BindingBacterial ProteinsComplement C1qComplement C3bCrl protein, Bacteriaamyloidcomplementcurli

Identifiers

PMID29364839
PMCPMC5871974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.