Evidence map›Paper›PMID 29364833›Full record

ReviewJournal of functional biomaterials2018

Hydrogels for Hydrophobic Drug Delivery. Classification, Synthesis and Applications.

Eneko Larrañeta, Sarah Stewart, Michael Ervine, Rehan Al-Kasasbeh, Ryan F Donnelly

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Injectable CaMaterials today. Bio · 2025
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eneko LarrañetaQueens University Belfast, School of Pharmacy, 97 Lisburn Road, Belfast BT9 7BL, UK. e.larraneta@qub.ac.uk.ORCID 0000-0003-3710-0438
Sarah StewartQueens University Belfast, School of Pharmacy, 97 Lisburn Road, Belfast BT9 7BL, UK. sstewart35@qub.ac.uk.
Michael ErvineQueens University Belfast, School of Pharmacy, 97 Lisburn Road, Belfast BT9 7BL, UK. mervine01@qub.ac.uk.
Rehan Al-KasasbehQueens University Belfast, School of Pharmacy, 97 Lisburn Road, Belfast BT9 7BL, UK.
Ryan F DonnellyQueens University Belfast, School of Pharmacy, 97 Lisburn Road, Belfast BT9 7BL, UK. r.donnelly@qub.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels have been shown to be very useful in the field of drug delivery due to their high biocompatibility and ability to sustain delivery. Therefore, the tuning of their properties should be the focus of study to optimise their potential. Hydrogels have been generally limited to the delivery of hydrophilic drugs. However, as many of the new drugs coming to market are hydrophobic in nature, new approaches for integrating hydrophobic drugs into hydrogels should be developed. This article discusses the possible new ways to incorporate hydrophobic drugs within hydrogel structures that have been developed through research. This review describes hydrogel-based systems for hydrophobic compound delivery included in the literature. The section covers all the main types of hydrogels, including physical hydrogels and chemical hydrogels. Additionally, reported applications of these hydrogels are described in the subsequent sections.

Indexed as

drug deliveryhydrogelshydrophobic drugsmicellesnanoparticlesphysical hydrogels

Identifiers

PMID29364833
PMCPMC5872099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.