ArticleParasite immunology2018
Intestinal parasites: Associations with intestinal and systemic inflammation.
Article in Parasite immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Burden of intestinal parasites among diabetic patients in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Intestinal parasitic infection among household contacts of primary cases, a comparative cross-sectional study.PloS one · 2019Trial
- Serum levels of Interleukin-10, Interleukin-6, and leptin in patients with Mycobacterium leprae-Helminth Co-Infections.BMC infectious diseases · 2025Observational
- Interplay of obesity and parasitic infection: current evidence of immunogenesis, tumorigenesis and leptin receptor involvement.Nutrition & metabolism · 2025Review
- Article
- Parasitic and Fungal Triggers of Cytokine Storm Syndrome.Advances in experimental medicine and biology · 2024Review
- Rural Embodiment and Community Health: an Anthropological Case Study on Biocultural Determinants of Tropical Disease Infection and Immune System Development in the USA.Current tropical medicine reports · 2023Review
- Intestinal parasites and diabetes: A systematic review and meta-analysis.New microbes and new infections · 2023Article
- Etiology of Persistent Microalbuminuria in Nigeria (P_MICRO study): protocol and study design.BMC infectious diseases · 2022Article
- Contribution of Schistosoma mansoni to systemic inflammation and microbial translocation among people with HIV in Zambia.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022Article
- A community-based, cross-sectional study to assess interactions between income, nutritional status and enteric parasitism in two Brazilian cities: are we moving positively towards 2030?Journal of health, population, and nutrition · 2021Article
- Epidemiology, species composition and genetic diversity of tetra- and octonucleated Entamoeba spp. in different Brazilian biomes.Parasites & vectors · 2021Article
- Intestinal parasites may be associated with later behavioral problems in internationally adopted children.PloS one · 2021Article
- Variation in Local and Systemic Pro-Inflammatory Immune Markers of Wild Wood Mice after Anthelmintic Treatment.Integrative and comparative biology · 2019Article
- Intestinal parasites: Associations with intestinal and systemic inflammation.Parasite immunology · 2018Article
- Risk Factor ofIranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to evaluate associations between intestinal parasitic infection with intestinal and systemic inflammatory markers in school-aged children with high rates of obesity. Plasma concentrations of C-Reactive Protein (CRP), leptin, TNF-α, IL-6 and IL-10 were measured as systemic inflammation markers and count of stool leukocytes as marker of intestinal inflammation in 291 children (6-10 years). Intestinal parasitic infection was measured by stool examination. Logistic regression analyses were performed to determine the odds of having high inflammatory markers for each parasite or group of parasites as compared to parasite-free children while adjusting for sex, age, mother's educational level and percentage of body fat. The prevalence of soil-transmitted helminths and intestinal protozoa infections was 12% and 36%, respectively. Parasitic infection was not associated with CRP, IL-6, IL-10 or TNF-α. Children infected with Ascaris lumbricoides (aOR: 5.91, 95% CI: 1.97-17.70) and Entamoeba coli (aOR: 8.46, 95% CI: 2.85-25.14) were more likely to have higher stool leucocytes than parasite-free children. Children with multiple infections (aOR: 10.60, 95% CI: 2.85-25.14) were more likely to have higher leptin concentrations than parasite-free children. Intestinal parasitic infection was not associated with systemic inflammation, but was associated with intestinal inflammation. Having multiple infections were associated with higher leptin concentrations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.