ArticleGenes2018
Exploring Genomic Variants Related to Residual Feed Intake in Local and Commercial Chickens by Whole Genomic Resequencing.
Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Untargeted metabolomic comparison of breast muscle metabolites between Cobb broilers and local chicken breeds.Poultry science · 2026Article
- Identification of central regulators related to residual feed intake in Huainan chickens based on weighted gene co-expression network analysis.Poultry science · 2026Article
- Residual Feed Intake as a Behavioral, Nutritional and Economic Criterion in Poultry Production.Animals : an open access journal from MDPI · 2025Review
- Genomic scans for selection and runs of homozygosity in southern Italian turkey populations.Poultry science · 2025Article
- Uncovering Molecular Mechanisms of Feed Efficiency in Pigs Through Multi-Omics Analysis of the Jejunum.Animals : an open access journal from MDPI · 2025Article
- Effect ofAnimals : an open access journal from MDPI · 2025Article
- Molecular genetic foundation of a sex-linked tailless trait in Hongshan chicken by whole genome data analysis.Poultry science · 2024Article
- The DuckAnimals : an open access journal from MDPI · 2023Article
- Genome-Wide Association Study of Feed Efficiency Related Traits in Ducks.Animals : an open access journal from MDPI · 2022Article
- Identification and characterization of circular RNAs in association with the feed efficiency in Hu lambs.BMC genomics · 2022Article
- Association of residual feed intake with growth performance, carcass traits, meat quality, and blood variables in native chickens.Journal of animal science · 2020Article
- Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks1.Journal of animal science · 2019Article
- A new chicken 55K SNP genotyping array.BMC genomics · 2019Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improving feed efficiency is a major goal in poultry production to reduce production costs and increase profitability. The genomic variants and possible molecular mechanisms responsible for residual feed intake (RFI) in chickens, however, remain poorly understood. In this study, using both local and commercial breeds, genome re-sequencing of low RFI and high RFI chickens was performed to elucidate the genomic variants underlying RFI. Results showed that 8,505,214 and 8,479,041 single nucleotide polymorphisms (SNPs) were detected in low and high RFI Beijing-You chickens, respectively; 8,352,008 and 8,372,769 SNPs were detected in low- and high-RFI Cobb chickens, respectively. Through a series of filtering processes, 3746 candidate SNPs assigned to 1137 genes in Beijing-You chickens and 575 candidate SNPs (448 genes) in Cobb chickens were found. The validation of the selected 191 SNPs showed that 46 SNPs were significantly associated with the RFI in an independent population of 779 Cobb chickens, suggesting that the method of screening associated SNPs with whole genome sequencing (WGS) strategy was reasonable. Functions annotation of RFI-related genes indicated that genes in Beijing-You were enriched in lipid and carbohydrate metabolism, as well as the phosphatase and tensin homolog (PTEN) signaling pathway. In Cobb, however, RFI-related genes were enriched in the feed behavior process and cAMP responsive element binding protein (CREB) signaling pathway. For both breeds, organismal development physiological processes were enriched. Correspondingly,
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