Evidence map›Paper›PMID 29363543›Full record

ArticleCancer research2018

Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ERα

Michael P Shea, Kathleen A O'Leary, Saja A Fakhraldeen, Vincent Goffin, Andreas Friedl, Kari B Wisinski, Caroline M Alexander, Linda A Schuler

Abstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
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  7. Article
  8. Review
  9. Review
  10. Prolactin: The Third Hormone in Breast Cancer.Frontiers in endocrinology · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Mapping Mammary Tumor Traits in the Rat.Methods in molecular biology (Clifton, N.J.) · 2019
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Michael P SheaMolecular and Environmental Toxicology Program, University of Wisconsin-Madison, Madison, Wisconsin.
Kathleen A O'LearyDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Saja A FakhraldeenDepartment of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Vincent GoffinInserm Unit 1151, Institut Necker Enfants Malades (INEM), Université Paris Descartes, Paris, France.
Andreas FriedlDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Kari B WisinskiUniversity of Wisconsin Paul P. Carbone Comprehensive Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.
Caroline M AlexanderDepartment of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Linda A SchulerDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin. linda.schuler@wisc.edu.
University of Wisconsin–Madison · USInserm · FR

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Molecular & Environmental Toxicology Pre-& Postdoctoral Training ProgramT32ES007015 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER A BRADFIELD · 1985 to 2026
$11.5M
Training in Cancer Biology Training GrantT32CA009135 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SUGDEN, WILLIAM M. · 1985 to 2024
$10.4M
Prolactin: mammary progenitors and tumor initiating cells in luminal carcinomasR01CA157675 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SCHULER, LINDA A. · 2011 to 2015
$1.5M
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA157675NCI NIH HHS T32 CA009135NIEHS NIH HHS T32 ES007015
6 · The paper itself

Abstract

Although antiestrogen therapies are successful in many patients with estrogen receptor alpha-positive (ERα

Indexed as

AdenocarcinomaAnimalsAntineoplastic Agents, HormonalBreast NeoplasmsCell PlasticityCell ProliferationEpithelial-Mesenchymal TransitionEstrogen Receptor alphaEstrogen Receptor AntagonistsFemaleFulvestrantHumansMammary Neoplasms, AnimalMiceNeoplastic Stem CellsProlactinAntineoplastic Agents, HormonalEstrogen Receptor alphaEstrogen Receptor AntagonistsFulvestrantProlactin

Identifiers

PMID29363543
PMCPMC5882549
OpenAlexW2790475640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.