Trial reportGut2019
Improved adenoma detection with Endocuff Vision: the ADENOMA randomised controlled trial.
Trial report in Gut, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
Adenoma Detection Rate Using Endocuff Vision in China
Computer-assisted Adenoma Detection Coloscopy With Endo-AID Artificial Intelligence System and Endocuff Versus Endocuff Assisted Colonoscopy: a Randomized Controlled Trial
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Effectiveness of artificial intelligence-assisted colonoscopy in detecting and diagnosing colorectal tumors: a systematic review and network meta-analysis.International journal of colorectal disease · 2025Pooled it
- Quality indicators for colonoscopy.Gastrointestinal endoscopy · 2024Guideline
- Pooled it
- Adenoma and Advanced Adenoma Detection Rates of Water Exchange, Endocuff, and Cap Colonoscopy: A Network Meta-Analysis with Pooled Data of Randomized Controlled Trials.Digestive diseases and sciences · 2021Pooled it
- Effect of Endocuff use on colonoscopy outcomes: A systematic review and meta-analysis.World journal of gastroenterology · 2019Pooled it
- Comparative study of endocuff assisted colonoscopy and artificial intelligence in colonoscopy in adenoma and polyp detection: a randomized, back-to-back study.BMC gastroenterology · 2025Trial
- Linked color imaging improves polyp miss rates in total colonoscopy in a multicenter randomized back to back trial.Scientific reports · 2025Trial
- Linked-color imaging with or without artificial intelligence for adenoma detection: a randomized trial.Endoscopy · 2024Trial
- Texture and color enhancement imaging (TXI) plus endocuff vision versus TXI alone for colorectal adenoma detection: a randomized controlled trial.Surgical endoscopy · 2023Trial
- Standard versus Endocuff versus cap-assisted colonoscopy for adenoma detection: A randomised controlled clinical trial.United European gastroenterology journal · 2021Trial
- Enhanced adenoma detection with Endocuff Vision: a GRADE assessed systematic review and meta-analysis.Clinical endoscopy · 2026Article
- Impact of Endocuff addition to real-time computer-aided detection of colorectal neoplasia in a randomised tandem colonoscopy trial.World journal of gastrointestinal pharmacology and therapeutics · 2026Article
- Colonoscopy Quality Indicators in Transition: From Adenoma Detection Rate to Serrated Lesion Detection and Beyond.Diagnostics (Basel, Switzerland) · 2026Review
- Randomized Trial of Hood With or Without Wing Attachment-Assisted Colonoscopy With Linked Color Imaging and Computer-Aided in Adenoma Detection.Endoscopy international open · 2026Article
- Artificial intelligence-assisted colonoscopy improves adenoma detection rates in routine colonoscopy practice: a single-center, retrospective, propensity score-matched study with concurrent controls.BMC gastroenterology · 2025Article
- Use of Mechanical Enhanced Colonoscopy to Improve Polyp Detection During Colorectal Cancer Screening: A Real-World Healthcare Database Analysis.Journal of clinical medicine · 2025Article
- Combining techniques and technologies increases adenoma detection rates in colonoscopy: More is more.World journal of gastrointestinal endoscopy · 2025Review
- Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing™-Assisted Colonoscopy: A Randomized Control Trial.Diagnostics (Basel, Switzerland) · 2025Article
- Effect of a distal attachment cuff on adenoma detection rate in screening colonoscopy: Randomized controlled trial in the Spanish population.Endoscopy international open · 2025Article
- Quality Indicators for Colonoscopy.The American journal of gastroenterology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveLow adenoma detection rates (ADR) are linked to increased postcolonoscopy colorectal cancer rates and reduced cancer survival. Devices to enhance mucosal visualisation such as Endocuff Vision (EV) may improve ADR. This multicentre randomised controlled trial compared ADR between EV-assisted colonoscopy (EAC) and standard colonoscopy (SC).
designPatients referred because of symptoms, surveillance or following a positive faecal occult blood test (FOBt) as part of the Bowel Cancer Screening Programme were recruited from seven hospitals. ADR, mean adenomas per procedure, size and location of adenomas, sessile serrated polyps, EV removal rate, caecal intubation rate, procedural time, patient experience, effect of EV on workload and adverse events were measured.
results1772 patients (57% male, mean age 62 years) were recruited over 16 months with 45% recruited through screening. EAC increased ADR globally from 36.2% to 40.9% (P=0.02). The increase was driven by a 10.8% increase in FOBt-positive screening patients (50.9% SC vs 61.7% EAC, P<0.001). EV patients had higher detection of mean adenomas per procedure, sessile serrated polyps, left-sided, diminutive, small adenomas and cancers (cancer 4.1% vs 2.3%, P=0.02). EV removal rate was 4.1%. Median intubation was a minute quicker with EAC (P=0.001), with no difference in caecal intubation rate or withdrawal time. EAC was well tolerated but caused a minor increase in discomfort on anal intubation in patients undergoing colonoscopy with no or minimal sedation. There were no significant EV adverse events.
conclusionEV significantly improved ADR in bowel cancer screening patients and should be used to improve colonoscopic detection. TRIAL REGISTRATION NUMBER: NCT02552017, Results; ISRCTN11821044, Results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.