Evidence map›Paper›PMID 29363325›Full record

ArticleAmerican journal of physiology. Renal physiology2018

Short-term high-glucose treatment decreased abundance of Orai1 protein through posttranslational mechanisms in rat mesangial cells.

Hui Jiang, Shubiao Zou, Sarika Chaudhari, Rong Ma

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. I-mfa, Mesangial Cell TRPC1 Channel, and Regulation of GFR.Journal of the American Society of Nephrology : JASN · 2025
    Article
  2. Article
  3. Review
  4. Enhanced Orai1-mediated store-operated CaThe Journal of biological chemistry · 2022
    Article
  5. Review
  6. miR-154-5p Affects the TGFOxidative medicine and cellular longevity · 2022
    Article
  7. Store-operated calcium entry: Pivotal roles in renal physiology and pathophysiology.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Hui JiangDepartment of Physiology and Anatomy, University of North Texas Health Science Center , Fort Worth, Texas.ORCID 0000-0002-5896-9178
Shubiao ZouDepartment of Physiology and Anatomy, University of North Texas Health Science Center , Fort Worth, Texas.
Sarika ChaudhariDepartment of Physiology and Anatomy, University of North Texas Health Science Center , Fort Worth, Texas.
Rong MaDepartment of Physiology and Anatomy, University of North Texas Health Science Center , Fort Worth, Texas.
University of North Texas · US

Funding

Store-operated Ca2+ signaling in kidney glomerular mesangial cellsR01DK115424 · NIDDK · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI MA, RONG · 2018 to 2021
$1.3M
American Heart Association-American Stroke Association 16GRNT27780043NIDDK NIH HHS R01 DK115424
6 · The paper itself

Abstract

The short-term effect of high-glucose (HG) treatment on store-operated Ca

Indexed as

AnimalsAntioxidantsCalcium SignalingCell Line, TransformedDose-Response Relationship, DrugDown-RegulationGlucoseHumansLysosomesMesangial CellsORAI1 ProteinOxidative StressProteasome Endopeptidase ComplexProteasome InhibitorsProtein StabilityProteolysisAntioxidantsGlucoseORAI1 ProteinORAI1 protein, humanOrai1 protein, ratProteasome Endopeptidase ComplexProteasome InhibitorsReactive Oxygen Specieshydrogen peroxidemesangial cellsOrai1store-operated Ca2+ entryubiquitination

Identifiers

PMID29363325
PMCPMC6031918
OpenAlexW2791402406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.