ArticleAddiction biology2019
Acupuncture inhibition of methamphetamine-induced behaviors, dopamine release and hyperthermia in the nucleus accumbens: mediation of group II mGluR.
Article in Addiction biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Coupling Bio-Resonance Neurotechnology (BRNT) and Dual Hemispheric Repetitive Transcranial Magnetic Stimulation (rTMS) Reduces Comorbid Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) as Demonstrated by PHQ-9 and GAD-7: Pilot Case Series.Psychology research and behavior management · 2025Article
- A synergistic effect of herb and acupuncture on the methamphetamine.Integrative medicine research · 2024Article
- Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model.International journal of molecular sciences · 2023Article
- Acupuncture for protracted amphetamine abstinence syndrome: study protocol for a systematic review and meta-analysis.BMJ open · 2023Article
- Mechanical Stimulation Alters Chronic Ethanol-Induced Changes to VTA GABA Neurons, NAc DA Release and Measures of Withdrawal.International journal of molecular sciences · 2022Article
- Effects of β-Phenylethylamine on Psychomotor, Rewarding, and Reinforcing Behaviors and Affective State: The Role of Dopamine D1 Receptors.International journal of molecular sciences · 2021Article
- Acupuncture Modulates Intracranial Self-Stimulation of the Medial Forebrain Bundle in Rats.International journal of molecular sciences · 2021Article
- Electroacupuncture prevents cocaine-induced conditioned place preference reinstatement and attenuates ΔFosB and GluR2 expression.Scientific reports · 2021Article
- Role of Lateral Hypothalamus in Acupuncture Inhibition of Cocaine Psychomotor Activity.International journal of molecular sciences · 2021Article
- Acupuncture Alleviates Anxiety and 22-kHz Ultrasonic Vocalizations in Rats Subjected to Repeated Alcohol Administration by Modulating the Brain-Derived Neurotrophic Factor/Corticotropin-Releasing Hormone Signaling Pathway.International journal of molecular sciences · 2021Article
- Paired mechanical and electrical acupuncture of neurogenic spots induces opioid-mediated suppression of hypertension in rats.The journal of physiological sciences : JPS · 2020Article
- Unpleasant Sound Elicits Negative Emotion and Reinstates Drug Seeking.Molecular neurobiology · 2019Article
- Effects of Acupuncture on Behavioral Stereotypies and Brain Dopamine System in Mice as a Model of Tourette Syndrome.Frontiers in behavioral neuroscience · 2019Article
- Peripheral Sensory Nerve Tissue but Not Connective Tissue Is Involved in the Action of Acupuncture.Frontiers in neuroscience · 2019Article
- Adjunctive PC6 magnetic stimulation with rTMS over left DLPFC for post-stroke cognitive impairment: a protocol for fNIRS-fMRI randomized controlled trial.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Methamphetamine (METH) increases metabolic neuronal activity in the mesolimbic dopamine (DA) system and mediates the reinforcing effect. To explore the underlying mechanism of acupuncture intervention in reducing METH-induced behaviors, we investigated the effect of acupuncture on locomotor activity, ultrasonic vocalizations, extracellular DA release in the nucleus accumbens (NAcs) using fast-scan cyclic voltammetry and alterations of brain temperature (an indicator of local brain metabolic activity) produced by METH administration. When acupuncture was applied to HT7, but not TE4, both locomotor activity and 50-kHz ultrasonic vocalizations were suppressed in METH-treated rats. Acupuncture at HT7 attenuated the enhancement of electrically stimulated DA release in the NAc of METH-treated rats. Systemic injection of METH produced a sustained increase in NAc temperature, which was reversed by the DA D1 receptor antagonist SCH 23390 or acupuncture at HT7. Acupuncture inhibition of METH-induced NAc temperature was prevented by pre-treatment with a group II metabotropic glutamate receptors (mGluR2/3) antagonist EGLU into the NAc or mimicked by injection of an mGluR2/3 agonist DCG-IV into the NAc. These results suggest that acupuncture reduces extracellular DA release and metabolic neuronal activity in the NAc through activation of mGluR2/3 and suppresses METH-induced affective states and locomotor behavior.
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