ReviewJournal of endocrinological investigation2018
New perspectives on the definition and management of polycystic ovary syndrome.
Review in Journal of endocrinological investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Association of PON1 gene polymorphisms with polycystic ovarian syndrome risk: a meta-analysis of case-control studies.Journal of endocrinological investigation · 2018Pooled it
- A Randomized Trial of the Efficacy of Three Weight Loss Diet Interventions in Overweight/Obese with Polycystic Ovary Syndrome.Endocrine, metabolic & immune disorders drug targets · 2024Trial
- Micronutrients in support to the one carbon cycle for the modulation of blood fasting homocysteine in PCOS women.Journal of endocrinological investigation · 2020Trial
- The effect of synbiotics pomegranate juice on cardiovascular risk factors in PCOS patients: a randomized, triple-blinded, controlled trial.Journal of endocrinological investigation · 2020Trial
- Natural Bioactive Compounds in Polycystic Ovary Syndrome: Properties, Molecular Mechanisms, and Therapeutic Potential.International journal of molecular sciences · 2026Review
- Association of Vascular Endothelial Growth Factor A-2549 I/D polymorphism with polycystic ovary syndrome susceptibility in Turkish women.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Idiopathic hirsutism: Is it really idiopathic or is it misnomer?World journal of clinical cases · 2023Review
- A brief insight into the etiology, genetics, and immunology of polycystic ovarian syndrome (PCOS).Journal of assisted reproduction and genetics · 2022Review
- Health system-related needs for healthy nutritional behaviors in adolescent girls with polycystic ovary syndrome (PCOS): a qualitative study in Iran.BMC health services research · 2022Article
- Endo&Art why Diana is depicted with mild androgenic alopecia?Journal of endocrinological investigation · 2022Article
- Insulin resistance and PCOS: chicken or egg?Journal of endocrinological investigation · 2021Review
- Hyperandrogenism by Liquid Chromatography Tandem Mass Spectrometry in PCOS: Focus on Testosterone and Androstenedione.Journal of clinical medicine · 2020Article
- MiRNAs expression profiling of rat ovaries displaying PCOS with insulin resistance.Archives of gynecology and obstetrics · 2020Article
- Clinical, hormonal and metabolic parameters in women with PCOS with different combined oral contraceptives (containing chlormadinone acetate versus drospirenone).Journal of endocrinological investigation · 2020Article
- Comprehensive genotyping of Turkish women with hirsutism.Journal of endocrinological investigation · 2019Article
- The resting metabolic rate in women with polycystic ovary syndrome and its relation to the hormonal milieu, insulin metabolism, and body fat distribution: a cohort study.Journal of endocrinological investigation · 2019Observational
- Relationship between surrogate estimates and direct measurement of insulin resistance in women with polycystic ovary syndrome.Journal of endocrinological investigation · 2019Article
- Association of SOD2 A16V and PON2 S311C polymorphisms with polycystic ovary syndrome in Chinese women.Journal of endocrinological investigation · 2019Article
- Effects of Metformin Treatment on Soluble Leptin Receptor Levels in Women with Polycystic Ovary Syndrome.Current medical science · 2019Article
- Elevation of isoprostanes in polycystic ovary syndrome and its relationship with cardiovascular risk factors.Journal of endocrinological investigation · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a growing debate on the opportunity of improving the understanding in the diagnosis and management of polycystic ovary syndrome (PCOS).
objectiveThis review article summarizes recent research related to the definition of polycystic ovary syndrome (PCOS).
methodsReview of the recent literature on the topic.
resultsNew ideas on the definition of hyperandrogenism, based on new scientific data and clinical perspectives are presented. (i) In fact, recent studies have pointed out the need to improve the concept of androgen excess by using a larger androgen profile, rather than simply measuring the testosterone blood levels. (ii) Due to the poor correlation between androgen blood levels and the degree of hirsutism, it is proposed that the definition of hyperandrogenism should be based on the presence of blood androgen excess and hirsutism, considered separately, because their pathophysiological mechanisms may differ according to the different phenotypes of PCOS. (iii) The potential role of obesity in favoring the development of PCOS during adolescence is also discussed and the concept of "PCOS secondary to obesity" is developed. (iv) Finally, the need for greater appropriateness in the evaluation of possible coexistence is highlighted, in patients with PCOS who have fasting or glucose-stimulated very high insulin levels, or severe insulin-resistant states.
conclusionsBased on what was discussed in this review, we believe that there are margins for modifying some of the current criteria that define the various PCOS phenotypes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.