Evidence map›Paper›PMID 29362972›Full record

ReviewJournal of industrial microbiology & biotechnology2018

Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape.

Raphael Ferreira, Florian David, Jens Nielsen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Precision Genome Editing with CRISPR-Cas9.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raphael FerreiraDepartment of Biology and Biological Engineering, Chalmers University of Technology, 412 96, Göteborg, Sweden.
Florian DavidDepartment of Biology and Biological Engineering, Chalmers University of Technology, 412 96, Göteborg, Sweden.
Jens NielsenDepartment of Biology and Biological Engineering, Chalmers University of Technology, 412 96, Göteborg, Sweden. nielsenj@chalmers.se.ORCID http://orcid.org/0000-0002-9955-6003

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR) is poised to become one of the key scientific discoveries of the twenty-first century. Originating from prokaryotic and archaeal immune systems to counter phage invasions, CRISPR-based applications have been tailored for manipulating a broad range of living organisms. From the different elucidated types of CRISPR mechanisms, the type II system adapted from Streptococcus pyogenes has been the most exploited as a tool for genome engineering and gene regulation. In this review, we describe the different applications of CRISPR/Cas9 technology in the industrial biotechnology field. Next, we detail the current status of the patent landscape, highlighting its exploitation through different companies, and conclude with future perspectives of this technology.

Indexed as

BiotechnologyClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene Expression RegulationBacteriophagesGene EditingGenetic EngineeringPatents as Topic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.