ArticleJournal of medical ultrasonics (2001)2018
Fusion imaging with contrast-enhanced ultrasonography for evaluating the early therapeutic efficacy of radiofrequency ablation for small hypervascular hepatocellular carcinomas with iso-echoic or unclear margins on conventional ultrasonography.
Article in Journal of medical ultrasonics (2001), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Diagnostic performance of contrast-enhanced ultrasonography for predicting therapeutic response to radiofrequency ablation in patients with hepatocellular carcinoma: a meta-analysis.Discover oncology · 2025Article
- Application and Evaluation of a 64-Slice CT Three-Dimensional Fusion Technique in the Determination of the Effective Ablation Margin after Radiofrequency Ablation of Hepatocellular Carcinoma.Computational and mathematical methods in medicine · 2022Article
- Abdominal Ultrasound and Treatment of Hepatocellular Carcinoma.Diagnostics (Basel, Switzerland) · 2021Article
- Comparison of Sonazoid contrast-enhanced ultrasound and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid MRI for the histological diagnosis of hepatocellular carcinoma.Quantitative imaging in medicine and surgery · 2021Article
- Use of Contrast-Enhanced Ultrasound with Sonazoid for Evaluating the Radiotherapy Efficacy for Hepatocellular Carcinoma.Diagnostics (Basel, Switzerland) · 2021Article
- Contrast-enhanced ultrasound as noninvasive diagnostic images that anyone can easily understand.Journal of medical ultrasonics (2001) · 2020Article
- The AFSUMB Consensus Statements and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound using Sonazoid.Ultrasonography (Seoul, Korea) · 2020Article
- On the occasion of publication of the feature on differential diagnosis and treatment of hepatocellular carcinoma: the role of ultrasound.Journal of medical ultrasonics (2001) · 2020Article
- Application of new ultrasound techniques for focal liver lesions.Journal of medical ultrasonics (2001) · 2020Review
- Clinical application of contrast-enhanced ultrasound after percutaneous renal tumor ablation.The British journal of radiology · 2019Article
- Real-time fusion-imaging in low back pain: a new navigation system for facet joint injections.La Radiologia medica · 2018Article
- The AFSUMB Consensus Statements and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound using Sonazoid.Journal of medical ultrasoundArticle
- Multimodality Imaging Evaluation of Hepatic Epithelioid Angiomyolipoma.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe evaluated the efficacy of fusion imaging combining contrast-enhanced ultrasonography (CEUS) images and arterial phase contrast-enhanced CT (CECT) or hepatobiliary phase magnetic resonance imaging with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (EOB-MRI) images for the early evaluation of the effectiveness of radiofrequency ablation (RFA) for small hypervascular hepatocellular carcinoma (HCC) with iso-echoic or unclear margins on conventional US.
methodsForty HCCs (22 iso-echoic and 18 unclear margin lesions) with mean diameters of 13.7 mm were treated using RFA under the guidance of fusion imaging with CEUS. The adequacy of RFA was evaluated using fusion imaging with CEUS 1 day after RFA. CECT or EOB-MRI was performed 1 month after RFA. We reviewed the images obtained using both modalities.
resultsWhen the 1-month CECT or EOB-MRI scans were used as the reference standard, the sensitivity, specificity, and accuracy of the 1-day fusion imaging for the diagnosis of the adequate ablation of these HCCs were 97, 100, and 98%, respectively; the kappa value for the agreement between the findings using the two modalities was 0.655.
conclusionFusion imaging with CEUS appears to be a useful method for the early evaluation of the efficacy of RFA for the treatment of HCCs with iso-echoic or unclear margins on conventional US.
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