Evidence map›Paper›PMID 29362929›Full record

Trial reportEuropean child & adolescent psychiatry2018

Does the efficacy of parent-child training depend on maternal symptom improvement? Results from a randomized controlled trial on children and mothers both affected by attention-deficit/hyperactivity disorder (ADHD).

Alexander Häge, Barbara Alm, Tobias Banaschewski, Katja Becker, Michael Colla, Christine Freitag, Julia Geissler, Alexander von Gontard, Erika Graf, Barbara Haack-Dees and 17 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European child & adolescent psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Are childhood and adult ADHD the same entities?European child & adolescent psychiatry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 8 institutions in 1 country.

Alexander HägeDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, J5, University of Heidelberg, 68159, Mannheim, Germany. alexander.haege@zi-mannheim.de.ORCID http://orcid.org/0000-0002-3434-2995
Barbara AlmDepartment of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.
Tobias BanaschewskiDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, J5, University of Heidelberg, 68159, Mannheim, Germany.
Katja BeckerDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, J5, University of Heidelberg, 68159, Mannheim, Germany.
Michael CollaDepartment of Psychiatry and Psychotherapy, Campus Benjamin Franklin, Charité, Universitätsmedizin Berlin, Berlin, Germany.
Christine FreitagDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Frankfurt University Hospital, Frankfurt am Main, Germany.
Julia GeisslerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, Germany.
Alexander von GontardDepartment of Child and Adolescent Psychiatry and Psychotherapy, Saarland University Hospital, Homburg, Germany.
Erika GrafClinical Trials Unit, Institute for Medical Biometry and Statistics, and Medical Faculty, Medical Center, University of Freiburg, Freiburg, Germany.
Barbara Haack-DeesDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.
Susann HänigDepartment of Child and Adolescent Psychiatry and Psychotherapy, Saarland University Hospital, Homburg, Germany.
Klaus HennighausenDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.
Sarah HohmannDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, J5, University of Heidelberg, 68159, Mannheim, Germany.
Christian JacobDepartment of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, Würzburg, Germany.
Charlotte JaiteDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Berlin, Germany.
Christine Jennen-SteinmetzDepartment of Biostatistics, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Viola KappelDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Berlin, Germany.
Swantje MatthiesDepartment of Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.
Alexandra PhilipsenDepartment of Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.
Luise PoustkaDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, J5, University of Heidelberg, 68159, Mannheim, Germany.
Wolfgang RetzFaculty of Medicine, Institute for Forensic Psychology and Psychiatry, Saarland University, Saarbrücken, Germany.
Michael RöslerFaculty of Medicine, Institute for Forensic Psychology and Psychiatry, Saarland University, Saarbrücken, Germany.
Katja Schneider-MommDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.
Esther SobanskiDepartment of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.
Timo D VloetDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, Germany.
Andreas WarnkeDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, Germany.
Thomas JansDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, Germany.
Heidelberg University · DEUniversity of Freiburg · DEUniversitätsklinikum Würzburg · DECharité - Universitätsmedizin Berlin · DESaarland University · DEJohannes Gutenberg University Mainz · DEGoethe University Frankfurt · DEPhilipps University of Marburg · DE

Funding

BMBF 01GV0605BMBF 01GV0606
6 · The paper itself

Abstract

Multimodal treatment of children with ADHD often includes parent-child training (PCT). However, due to the high heritability, parents of children with ADHD are frequently also affected by the disorder, which is likely to constitute a significant barrier to successful treatment of the child. This secondary analysis of our randomized controlled multicentre AIMAC trial (ADHD in mothers and children) investigates whether children's outcomes following parent-child training in combination with maternal ADHD treatment depend on maternal symptom improvement. In a first step focusing on treatment of maternal ADHD, 144 mothers of mother-child dyads were randomized to multimodal ADHD treatment (group psychotherapy plus methylphenidate) or clinical management (mainly supportive counselling). After 12 weeks (T2), a 12-week PCT program (T2-T3) for all mother-child dyads was added to treat children's ADHD. Maternal symptomatology (CAARS-O:L; SCL-90-R) and children's externalizing symptoms (ADHD-ODD Scale, SDQ) were repeatedly assessed (T1 = baseline, T2, T3). Effects of changes in maternal symptomatology (T1-T2) on the change in children's symptom scores (T1-T3) were analysed using a general linear model, controlling for baseline scores, study centre, and maternal treatment group. 125 mother-child dyads were analysed. Mothers showed significant improvements in ADHD symptoms and overall psychopathology [CAARS-O:L ADHD index: mean - 3.54, SE 0.74 p < 0.0001; SCL-90-R Global Severity (GS): mean - 11.03, SE 3.90, p = 0.0056]. Although children's externalizing symptoms improved significantly (ADHD-ODD Scale: mean - 4.46, SE 0.58, p < 0.0001), maternal improvement had no effect on children's outcomes after Bonferroni-Holm correction for multiple testing. The findings do not support our hypothesis that children's outcomes following PCT for ADHD depend on maternal symptom improvements.Trial register CCT-ISRCTN73911400.

Indexed as

Attention Deficit Disorder with HyperactivityChildChild, PreschoolFemaleHumansMaleMothersPsychotherapyMaternal ADHDParent–child trainingTreatment response

Identifiers

PMID29362929
OpenAlexW2788896361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.