Evidence map›Paper›PMID 29362869›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2018

Antiplatelet and anticoagulant agents in vitreoretinal surgery: a prospective multicenter study involving 804 patients.

Cyril Meillon, Pierre Henry Gabrielle, Maxime Luu, Ludwig S Aho-Glele, Alain M Bron, Catherine Creuzot-Garcher, CFSR research net

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Perioperative Management of Anticoagulants in Ocular Surgeries.International ophthalmology clinics · 2020
    Article
  5. Safety of cataract surgery in patients treated with the new oral anticoagulants (NOACs).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  6. Antiplatelet and anticoagulant agents in vitreoretinal surgery: a prospective multicenter study involving 804 patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  7. Dual antiplatelet therapy may lead to hemorrhagic complications in vitrectomy of proliferative diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  8. Antiplatelet and anticoagulant agents in vitreoretinal surgery: a prospective multicenter study involving 804 patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  9. [Management of anticoagulants in ophthalmic surgery-a survey among ophthalmic surgeons in Germany].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2018
    Article
  10. Antiplatelet and anticoagulant agents in vitreoretinal surgery: a prospective multicenter study involving 804 patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Cyril MeillonDepartment of Ophthalmology, University Hospital, 14 rue Paul Gaffarel, 21079, Dijon, France.
Pierre Henry GabrielleDepartment of Ophthalmology, University Hospital, 14 rue Paul Gaffarel, 21079, Dijon, France.
Maxime LuuPlurithematic Clinical Investigation Center (CIC-P) INSERM 803 and Department of Medical Pharmacology, University Hospital, Dijon, France.
Ludwig S Aho-GleleHospital Hygiene and Epidemiology Unit, University Hospital, Dijon, France.
Alain M BronDepartment of Ophthalmology, University Hospital, 14 rue Paul Gaffarel, 21079, Dijon, France. alain.bron@chu-dijon.fr.ORCID http://orcid.org/0000-0002-7265-931X
Catherine Creuzot-GarcherDepartment of Ophthalmology, University Hospital, 14 rue Paul Gaffarel, 21079, Dijon, France.
CFSR research net
Centre National de la Recherche Scientifique · FRMaison des Sciences sociales et des Humanités de Dijon · FRCHU Dijon Bourgogne · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the rate of hemorrhagic complications after vitreoretinal surgery and the influence of antithrombotic agents.

methodsHemorrhagic complications of vitreoretinal procedures performed in seven ophthalmologic centers on patients treated or not treated with antiplatelet (AP) or anticoagulant (AC) agents were prospectively collected. Patients' characteristics, surgical techniques, and complications were recorded during surgery and for 1 month after.

resultsEight hundred four procedures were performed between January 2015 and April 2015. Among them, 18.4% were treated with AP agents (n = 148) and 7.8% with AC agents (n = 63), with 18 of them treated with NOACS (new oral anticoagulants). AP or AC agents were continued in 96.5% and 80.7% of cases, respectively. Fifty-three patients (6.6%) developed one or more hemorrhagic complications in one eye during this period. In univariate analysis, AC agents were not associated with hemorrhagic complications (P = 0.329) in contrast to AP (P = 0.005). However, in multivariate analysis, AP agents were no longer associated with hemorrhagic complications and the intraoperative use of endodiathermy was the only factor associated with hemorrhagic complications (P = 0.001).

conclusionsThis study showed that AP and AC agents were not a factor associated with hemorrhagic complications during vitreoretinal surgery. The continuation of these treatments should be considered without risk of severe hemorrhagic complications.

Indexed as

AgedAnticoagulantsBlood CoagulationFemaleFollow-Up StudiesFranceHumansIncidenceMalePlatelet Aggregation InhibitorsPostoperative HemorrhageProspective StudiesRetinal DiseasesRisk FactorsVitreoretinal SurgeryAnticoagulantsPlatelet Aggregation InhibitorsAnticoagulantsAntiplatelet agentsAntithrombotic therapyVitreoretinal surgery

Identifiers

PMID29362869
OpenAlexW4231729933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.