ArticleERJ open research2018
Decrease in pulmonary function and oxygenation after lung resection.
Article in ERJ open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04807153 (Exercise Capacity, Pulmonary Function and Physical Activity Levels in Patients With Lung Cancer Undergoing Pneumonectomy), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise Capacity, Pulmonary Function and Physical Activity Levels in Patients With Lung Cancer Undergoing Pneumonectomy
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Recruitment maneuvers in patients undergoing thoracic surgery: a meta-analysis.General thoracic and cardiovascular surgery · 2021Pooled it
- Physical activity, functional capacity, and mental health during the first postoperative month in patients undergoing ambulatory pulmonary wedge resection: a prospective observational study.BMC pulmonary medicine · 2026Observational
- Factors Affecting Exercise Tolerance in Patients Who Underwent Video-Assisted Thoracoscopic Surgery for Lung Cancer.Cureus · 2025Article
- The impact of lung surgery, with or without (neo-)adjuvant therapy, on physical functioning in patients with nonsmall cell lung cancer: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2025Article
- Is Spirometry a Sufficient Test for Assessing Respiratory Function after Lung Resection?Current oncology (Toronto, Ont.) · 2024Article
- Comparison of Early Postoperative Diaphragm Muscle Function after Lobectomy via VATS and Open Thoracotomy: A Sonographic Study.Life (Basel, Switzerland) · 2024Article
- Applying ICF Framework to Explore the Factors That Influence Quality of Life in Patients After Lung Surgery.Annals of rehabilitation medicine · 2024Article
- Effect of lung rehabilitation training combined with nutritional intervention on patients after thoracoscopic resection of lung cancer.Oncology letters · 2024Article
- Chronic obstructive pulmonary disease assessment test for the measurement of deterioration and recovery of health status of patients undergoing lung surgery.Thoracic cancer · 2022Article
- Physical function and health-related quality of life in the convalescent phase in surgically treated patients with malignant pleural mesothelioma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Effect of Intraoperative Dexmedetomidine on Postoperative Pain and Pulmonary Function Following Video-assisted Thoracoscopic Surgery.Anesthesia, essays and researchesArticle
- Factors Influencing Functional Exercise Capacity After Lung Resection for Non-Small Cell Lung Cancer.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory deficits are common following curative intent lung cancer surgery and may reduce the patient's ability to be physically active. We evaluated the influence of surgery on pulmonary function, respiratory muscle strength and physical performance after lung resection. Pulmonary function, respiratory muscle strength (maximal inspiratory/expiratory pressure) and 6-min walk test (6MWT) were assessed pre-operatively, 2 weeks post-operatively and 6 months post-operatively in 80 patients (age 68±9 years). Video-assisted thoracoscopic surgery was performed in 58% of cases. Two weeks post-operatively, we found a significant decline in pulmonary function (forced vital capacity -0.6±0.6 L and forced expiratory volume in 1 s -0.43±0.4 L; both p<0.0001), 6MWT (-37.6±74.8 m; p<0.0001) and oxygenation (-2.9±4.7 units; p<0.001), while maximal inspiratory and maximal expiratory pressure were unaffected. At 6 months post-operatively, pulmonary function and oxygenation remained significantly decreased (p<0.001), whereas 6MWT was recovered. We conclude that lung resection has a significant short- and long-term impact on pulmonary function and oxygenation, but not on respiratory muscle strength. Future research should focus on mechanisms negatively influencing post-operative pulmonary function other than impaired respiratory muscle strength.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.