Evidence map›Paper›PMID 29362596›Full record

Trial reportJournal of medicine and life

Cerebrolysin and early neurorehabilitation in patients with acute ischemic stroke: a prospective, randomized, placebo-controlled clinical study.

A Stan, C Birle, A Blesneag, M Iancu

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06052787 (The Impact and Outcomes of Combined Cerebrolysin and Amantadine Sulfate Administration on Management of Patients With Traumatic Brain Injury in the ICU), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06052787 phase3completednot on this map

The Impact and Outcomes of Combined Cerebrolysin and Amantadine Sulfate Administration on Management of Patients With Traumatic Brain Injury in the ICU

TypeinterventionalSponsorAin Shams UniversityRan2023 to 2025Enrolled150ConditionsTraumatic Brain InjuryArmsCerebrolysin, amantadine sulfate
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Cerebrolysin for acute ischaemic stroke.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Research in the Acute Rehabilitation Setting: a Bridge Too Far?Current neurology and neuroscience reports · 2019
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

A StanDepartment of Clinical Neurosciences, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
C BirleRoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.
A BlesneagDepartment of Clinical Neurosciences, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
M IancuDepartment of Medical Informatics and Biostatistics, Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROResearch Institute for Analytical Instrumentation · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neurological RehabilitationAgedAmino AcidsBrain IschemiaDemographyDouble-Blind MethodFemaleHumansMaleMiddle AgedNeuroprotective AgentsPlacebosProspective StudiesRisk FactorsStrokeTreatment OutcomeAmino AcidscerebrolysinNeuroprotective AgentsPlacebosacute strokeCerebrolysinearly neurorehabilitationneurorecoveryneurotrophic factors

Identifiers

PMID29362596
PMCPMC5771251
OpenAlexW2982012874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.