Evidence map›Paper›PMID 29362486›Full record

ArticleScientific reports2018

Virtual craniotomy for high-resolution optoacoustic brain microscopy.

Héctor Estrada, Xiao Huang, Johannes Rebling, Michael Zwack, Sven Gottschalk, Daniel Razansky

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Photoacoustic imaging for microcirculation.Microcirculation (New York, N.Y. : 1994) · 2022
    Review
  6. Review
  7. Article
  8. Article
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  16. Imaging the aged brain: pertinence and methods.Quantitative imaging in medicine and surgery · 2019
    Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Héctor EstradaInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany. hector.estrada@posteo.org.ORCID http://orcid.org/0000-0002-4345-6695
Xiao HuangInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany.
Johannes ReblingInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany.
Michael ZwackInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany.
Sven GottschalkInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany.
Daniel RazanskyInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany. dr@tum.de.
Helmholtz Zentrum München · DE

Funding

European Research Council 682379
6 · The paper itself

Abstract

Ultrasound-mediated transcranial images of the brain often suffer from acoustic distortions produced by the skull bone. In high-resolution optoacoustic microscopy, the skull-induced acoustic aberrations are known to impair image resolution and contrast, further skewing the location and intensity of the different absorbing structures. We present a virtual craniotomy deconvolution algorithm based on an ultrasound wave propagation model that corrects for the skull-induced distortions in optically-resolved optoacoustic transcranial microscopy data. The method takes advantage of the geometrical and spectral information of a pulse-echo ultrasound image of the skull simultaneously acquired by our multimodal imaging system. Transcranial mouse brain imaging experiments confirmed the ability to accurately account for the signal amplitude decay, temporal delay and pulse broadening introduced by the rodent's skull. Our study is the first to demonstrate skull-corrected transcranial optoacoustic imaging in vivo.

Indexed as

AlgorithmsAnimalsBrainCraniotomyHumansMiceMicroscopy, AcousticMultimodal ImagingPhotoacoustic TechniquesUser-Computer Interface

Identifiers

PMID29362486
PMCPMC5780415
OpenAlexW2806667582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.