ReviewNature reviews. Gastroenterology & hepatology2018
Role of priority effects in the early-life assembly of the gut microbiota.
Review in Nature reviews. Gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 227 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
227 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From Microbial Dynamics to Functionality in the Rhizosphere: A Systematic Review of the Opportunities With Synthetic Microbial Communities.Frontiers in plant science · 2021Pooled it
- Trial
- The Effect of Weaning with Adult Food Typical of the Mediterranean Diet on Taste Development and Eating Habits of Children: A Randomized Trial.Nutrients · 2022Trial
- Maternal obesity alters human milk oligosaccharides content and correlates with early acquisition of late colonizers in the neonatal gut microbiome.Gut microbes · 2026Article
- The Critical Period Microbiota Shape Brain Plasticity.Research square · 2026Article
- Fermented corn germ meal modulates intestinal inflammation and influences gut microbial succession in broiler chickens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Impact of Infant Feeding Mode on Gut Microbiome Composition in Early Life: Evidence from an Egyptian Cohort.Scientific reports · 2026Article
- Maternal and infant gut microbiome.iMeta · 2026Review
- Early-life stress and adolescent circadian dysrhythmia drives unique behavioral and microbial profiles in rats.BMC microbiology · 2026Article
- The Critical Period Microbiota Shape Brain Plasticity.bioRxiv : the preprint server for biology · 2026Article
- Stool Dynamics and the Developing Gut Microbiome During Infancy.Journal of biological rhythms · 2026Article
- Historical Contingency Drives Freshwater Microbial Community Assembly Across Successional Time.Ecology and evolution · 2026Article
- Consistent, Scale-Dependent Differences in the Biogeography of Host-Associated and Free-Living Microbiomes Across Systems.Molecular ecology · 2026Article
- Temperature at parental generation affects bacterial communities associated with offspring for both host and parasitoid.FEMS microbiology ecology · 2026Article
- Early-Life Iron Exposure Influences Long-Term Gut Microbiota Recovery After Intestinal Dysbiosis.Microorganisms · 2026Article
- Cariogenic microorganisms induce oral epithelial atypia through host-microbiome-high sugar diet interactions.NPJ biofilms and microbiomes · 2026Article
- Article
- Priority effects drive strain-level community composition of honeybee gut microbiota.The ISME journal · 2026Article
- Caenorhabditis elegans as an experimental model for resilience-boosting microbiota interventions in nonmodel ectotherms.FEMS microbiology reviews · 2026Review
- Off to a good start: current gaps and priorities in early-life microbiome research.FEMS microbiology reviews · 2026Review
167 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Understanding how microbial communities develop is essential for predicting and directing their future states. Ecological theory suggests that community development is often influenced by priority effects, in which the order and timing of species arrival determine how species affect one another. Priority effects can have long-lasting consequences, particularly if species arrival history varies during the early stage of community development, but their importance to the human gut microbiota and host health remains largely unknown. Here, we explore how priority effects might influence microbial communities in the gastrointestinal tract during early childhood and how the strength of priority effects can be estimated from the composition of the microbial species pool. We also discuss factors that alter microbial transmission, such as delivery mode, diet and parenting behaviours such as breastfeeding, which can influence the likelihood of priority effects. An improved knowledge of priority effects has the potential to inform microorganism-based therapies, such as prebiotics and probiotics, which are aimed at guiding the microbiota towards a healthy state.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.