ArticleTranslational psychiatry2018
The real-life costs of emotion regulation in anorexia nervosa: a combined ecological momentary assessment and fMRI study.
Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Neuroscience meets behavior: A systematic literature review on magnetic resonance imaging of the brain combined with real-world digital phenotyping.Human brain mapping · 2024Pooled it
- Youth Psychopathology in Daily Life: Systematically Reviewed Characteristics and Potentials of Ecological Momentary Assessment Applications.Child psychiatry and human development · 2022Pooled it
- The association between childhood traumatic events and weight restoration in adult anorexia nervosa inpatient treatment: a longitudinal study.Eating and weight disorders : EWD · 2026Article
- Shared and disorder-specific resting-state neural activity characteristics in patients with anorexia nervosa and bulimia nervosa.Journal of eating disorders · 2026Article
- Neural correlates of affective self-positivity bias in first and second languages.Frontiers in psychology · 2026Article
- Does Evidence Support an Emotion Regulation Model of Anorexia Nervosa? A Systematic Review of Over a Decade of Research.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025Article
- Cognitive and emotional processing in brothers of individuals with anorexia nervosa: exploring familial cognitive vulnerability.Frontiers in psychiatry · 2025Article
- Neuroimaging studies of resting-state functional magnetic resonance imaging in eating disorders.BMC medical imaging · 2024Review
- The Willpower Paradox: Possible and Impossible Conceptions of Self-Control.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- Difficulties with positive emotion regulation in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2023Article
- A neural network underlying cognitive strategies related to eating, weight and body image concerns.Frontiers in human neuroscience · 2023Article
- Therapy outcome of day treatment for people with anorexia nervosa before and during the COVID-19 pandemic.Brain and behavior · 2022Article
- Intact neural and behavioral correlates of emotion processing and regulation in weight-recovered anorexia nervosa: a combined fMRI and EMA study.Translational psychiatry · 2022Article
- A 1-year follow-up study of the longitudinal interplay between emotion dysregulation and childhood trauma in the treatment of anorexia nervosa.The International journal of eating disorders · 2022Article
- Examining prospective mediational relationships between momentary rumination, negative affect, and binge eating using ecological momentary assessment.Journal of affective disorders reports · 2021Article
- The Maudsley Anorexia Nervosa Treatment for Adults (MANTRA): a feasibility case series of an integrated group based approach.Journal of eating disorders · 2021Article
- The costs of over-control in anorexia nervosa: evidence from fMRI and ecological momentary assessment.Translational psychiatry · 2021Article
- Article
- Autonomic Nervous System Response to Psychosocial Stress in Anorexia Nervosa: A Cross-Sectional and Controlled Study.Frontiers in psychology · 2021Article
- Exploring Neural Mechanisms Related to Cognitive Control, Reward, and Affect in Eating Disorders: A Narrative Review of FMRI Studies.Neuropsychiatric disease and treatment · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regulation of emotions is necessary for successful attainment of short-term and long-term goals. However, over-regulation may also have its costs. In anorexia nervosa (AN), forgoing food intake despite emaciation and endocrine signals that promote eating is an example of "too much" self-control. Here we investigated whether voluntary emotion regulation in AN patients comes with associated disorder-relevant costs. Thirty-five patients with acute AN and thirty-five age-matched healthy controls (HCs) performed an established emotion regulation paradigm during functional magnetic resonance imaging after an overnight fast. The task required reducing emotions induced by positively valenced pictures via distancing. We calculated a neural regulation score from responses recorded in a reward-related brain region of interest (ventral striatum; VS) by subtracting activation measured on "positive distance" trials from that elicited under the "positive watch" (baseline) condition. Complementing the imaging data, we used ecological momentary assessment (EMA) to probe disorder-related rumination and affect six times/day for 2 weeks following the scanning session. The neural regulation score indicating reduced VS activation during emotion regulation was used as a predictor in hierarchical linear models with EMA measures as outcomes. No group differences in neural activity were found for the main contrasts of the task. However, regulation of VS activity was associated with increased body-related rumination and increased negative affect in AN, but not in HC. In line with this finding, correlational analysis with longitudinal BMI measurements revealed a link between greater VS regulation and poorer treatment outcome after 60 and 90 days. Together, these results identify a neural correlate of altered emotion regulation in AN, which seems to be detrimental to psychological well-being and may interfere with recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.