Evidence map›Paper›PMID 29362238›Full record

ArticlemBio2018

Adaptive Evolution of RH5 in Ape

Lindsey J Plenderleith, Weimin Liu, Oscar A MacLean, Yingying Li, Dorothy E Loy, Sesh A Sundararaman, Frederic Bibollet-Ruche, Gerald H Learn, Beatrice H Hahn, Paul M Sharp

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023
    Review
  5. Article
  6. Review
  7. Ape Origins of Human Malaria.Annual review of microbiology · 2020
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Lindsey J PlenderleithInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom.
Weimin LiuDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Oscar A MacLeanInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom.
Yingying LiDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Dorothy E LoyDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sesh A SundararamanDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Frederic Bibollet-RucheDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Gerald H LearnDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Beatrice H HahnDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Paul M SharpInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom paul.sharp@ed.ac.uk.
University of Pennsylvania · USCentre for Immunity, Infection and Evolution · GBUniversity of Edinburgh · GB

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Natural SIV Reservoirs and Human Zoonotic RiskR37AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2008 to 2017
$5.7M
Great Ape Reservoirs of Human MalariaR01AI091595 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2011 to 2019
$5.3M
PARASITOLOGY: MODERN APPROACHEST32AI007532 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 1998 to 2022
$5.0M
Studies of the precursor of the human AIDS virus in its natural chimpanzee hostR01AI120810 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2016 to 2020
$3.4M
Biotechnology and Biological Sciences Research Council BB/M010996/1NIAID NIH HHS P30 AI045008NIAID NIH HHS R01 AI091595NIAID NIH HHS R01 AI120810NIAID NIH HHS R37 AI050529NIAID NIH HHS T32 AI007532
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Evolution, MolecularAnimalsApe DiseasesBasiginBinding SitesHominidaeHumansMalariaPlasmodiumProtein BindingProtozoan ProteinsSelection, GeneticBasiginProtozoan ProteinsbasiginchimpanzeegorillaLaveraniaPlasmodium falciparumRH5

Identifiers

PMID29362238
PMCPMC5784257
OpenAlexW2789087138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.