Evidence map›Paper›PMID 29362230›Full record

ArticlemBio2018

Contrasting Function of Structured N-Terminal and Unstructured C-Terminal Segments of

Javeed Ahmad, Aisha Farhana, Rita Pancsa, Simran Kaur Arora, Alagiri Srinivasan, Anil Kumar Tyagi, Madan Mohan Babu, Nasreen Zafar Ehtesham, Seyed Ehtesham Hasnain

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. The PE/PPE family proteins ofFrontiers in immunology · 2025
    Review
  3. Article
  4. Article
  5. Expression of a uniqueFrontiers in microbiology · 2024
    Article
  6. Review
  7. Review
  8. Different modalities of host cell death and their impact onAmerican journal of physiology. Cell physiology · 2022
    Review
  9. Review
  10. TheInternational journal of molecular sciences · 2022
    Review
  11. Frontiers in immunology · 2022
    Article
  12. Review
  13. PGRS Domain of Rv0297 ofInternational journal of molecular sciences · 2021
    Article
  14. Frontiers in immunology · 2021
    Article
  15. Frontiers in immunology · 2021
    Article
  16. Frontiers in cellular and infection microbiology · 2020
    Article
  17. PGRS Domain of Rv0297 ofFrontiers in cellular and infection microbiology · 2020
    Article
  18. ImmunodominantFrontiers in immunology · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Javeed Ahmad *Inflammation Biology and Cell Signaling Laboratory, National Institute of Pathology, New Delhi, India.
Aisha Farhana *Laboratory of Molecular and Cellular Biology, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India.
Rita PancsaMedical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
Simran Kaur AroraInflammation Biology and Cell Signaling Laboratory, National Institute of Pathology, New Delhi, India.
Alagiri SrinivasanDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Anil Kumar TyagiDepartment of Biochemistry, University of Delhi South Campus, New Delhi, India.
Madan Mohan BabuMedical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom madanm@mrc-lmb.cam.ac.uk nzehtesham@gmail.com seyedhasnain@gmail.com.
Nasreen Zafar EhteshamInflammation Biology and Cell Signaling Laboratory, National Institute of Pathology, New Delhi, India madanm@mrc-lmb.cam.ac.uk nzehtesham@gmail.com seyedhasnain@gmail.com.
Seyed Ehtesham HasnainMolecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, India madanm@mrc-lmb.cam.ac.uk nzehtesham@gmail.com seyedhasnain@gmail.com.
National Institute of Pathology · INMedical Research Council · GBAll India Institute of Medical Sciences · INCentre for DNA Fingerprinting and Diagnostics · INJamia Hamdard · INUniversity of Delhi · IN

Funding

Medical Research Council MC_U105185859
6 · The paper itself

Abstract

Pathogens frequently employ eukaryotic linear motif (ELM)-rich intrinsically disordered proteins (IDPs) to perturb and hijack host cell networks for a productive infection.

Indexed as

Antibodies, BacterialApoptosisBacterial ProteinsCells, CulturedDendritic CellsHumansImmunoglobulin GIron-Binding ProteinsMacrophagesMembrane ProteinsMonocytesMycobacterium tuberculosisTuberculosisAntibodies, BacterialBacterial ProteinsImmunoglobulin GIron-Binding ProteinsMembrane ProteinsPPE37 protein, Mycobacterium tuberculosisapoptosiseukaryotic linear motifshost-pathogen interactionsintrinsically disordered regionsmolecular mimicrynuclear localization signaltolerogenic immune cells

Identifiers

PMID29362230
PMCPMC5784249
OpenAlexW2790691782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.