Evidence map›Paper›PMID 29362228›Full record

ArticleEndocrine connections2018

Maternal exposure to UV filters: associations with maternal thyroid hormones, IGF-I/IGFBP3 and birth outcomes.

M Krause, H Frederiksen, K Sundberg, F S Jørgensen, L N Jensen, P Nørgaard, C Jørgensen, P Ertberg, J H Petersen, U Feldt-Rasmussen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. The MAK collection for occupational health and safety · 2026
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  6. Prenatal exposure to multiple environmental chemicals and birth size.Journal of exposure science & environmental epidemiology · 2024
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

M KrauseDepartment of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC)Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
H FrederiksenDepartment of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC)Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
K SundbergCenter of Fetal Medicine and PregnancyDepartment of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
F S JørgensenFetal Medicine UnitDepartment of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark.
L N JensenCenter of Fetal Medicine and PregnancyDepartment of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
P NørgaardFetal Medicine UnitDepartment of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark.
C JørgensenCenter of Fetal Medicine and PregnancyDepartment of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
P ErtbergFetal Medicine UnitDepartment of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark.
J H PetersenDepartment of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC)Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
U Feldt-RasmussenDepartment of EndocrinologyRigshospitalet, University of Copenhagen, Copenhagen, Denmark.
A JuulDepartment of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC)Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
K T DrzewieckiDepartment of Plastic SurgeryBreast Surgery and Burns Treatment, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
N E SkakkebaekDepartment of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC)Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
A M AnderssonDepartment of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC)Rigshospitalet, University of Copenhagen, Copenhagen, Denmark Anna-Maria.Andersson@regionh.dk.
Rigshospitalet · DKCopenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral chemical UV filters/absorbers ('UV filters' hereafter) have endocrine-disrupting properties

objectivesTo examine maternal exposure to UV filters, associations with maternal thyroid hormone, with growth factor concentrations as well as to birth outcomes.

methodsProspective study of 183 pregnant women with 2nd trimester serum and urine samples available. Maternal concentrations of the chemical UV filters benzophenone-1 (BP-1) and benzophenone-3 (BP-3) in urine and 4-hydroxy-benzophenone (4-HBP) in serum were measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The relationships between 2nd trimester maternal concentrations of the three chemical UV filters and maternal serum concentrations of thyroid hormones and growth factors, as well as birth outcomes (weight, height, and head and abdominal circumferences) were examined.

resultsPositive associations between maternal serum concentrations of 4-HBP and triiodothyronine (T

conclusionsWidespread exposure of pregnant women to chemical UV filters and the possible impact on maternal thyroid hormones and growth factors, and on fetal growth, calls for further studies on possible long-term consequences of the exposure to UV filters on fetal development and children's health.

Indexed as

4-hydroxy-benzophenone (4-HBP)birth outcomegrowth factorsthyroid hormonesUV filters

Identifiers

PMID29362228
PMCPMC5820990
OpenAlexW2792421965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.